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Ginger Extract (Zingiber officinale)
Gingerols and shogaols reduce nausea, accelerate gastric emptying, and provide systemic anti-inflammatory benefits.
What the evidence says
Ginger Extract appears to help in 4 of 4 studies with measurable effects — the evidence leans clearly favourable.
Most evidence is from high-quality meta-analyses and randomised trials published 1986–2026 with a typical study size of 508 participants.
Based on 115 studies · 20 meta-analyses · 56 RCTs · 15,372 total participants
Confidence
High confidenceWhat the studies found
By outcome
Multiple meta-analyses and an umbrella review give high-confidence support for antiemetic effects in pregnancy, plus consistent benefits for dysmenorrhea pain and inflammatory markers; weaker or mixed glycemic and weight data keep it at Strong rather than higher.
55 randomised trials
every one checked individually
Every randomised or controlled trial of Ginger Extract indexed in PubMed, not a hand-picked subset. Meta-analyses and systematic reviews are deliberately excluded from this count: most of them cover many compounds at once, so counting them would inflate it.
PubMed · as of Jul 2026
49 trials ongoing or recruiting · 134 completed on ClinicalTrials.gov
7 of the completed trials have posted results
Registered trials show research momentum for Ginger Extract, not proof of effect — a registration is a plan, and posted results are sponsor-reported, not peer-reviewed. They are never counted toward the evidence rating above.
Browse these trials on ClinicalTrials.govClinicalTrials.gov · as of Oct 2026
Ginger has been used for thousands of years across cultures for digestive complaints. Modern research strongly supports its efficacy for nausea (especially pregnancy-related and motion sickness), improved gastric emptying, and anti-inflammatory effects.
The active compounds gingerols and shogaols provide most of its therapeutic benefits.
Blocks serotonin receptors in the gut
Speeds gastric emptying
Reduces inflammation throughout the body
How Ginger Extract works — from molecular targets to health outcomes. Click an edge to see supporting research.This visualization is in beta — pathways are being refined and expanded.
Well-studied for morning sickness; keep under 1g/day
A clinically important interaction between ginger extract and each listed anticoagulant or antiplatelet medicine has not been established from the evidence supplied here. Ask a pharmacist to assess the exact supplement, medicine and other bleeding risks before use. This possible interaction has not been individually evaluated for this supplement; its likelihood and severity are unknown. If you take an anticoagulant or antiplatelet medicine, ask a pharmacist or prescriber before using this product. Do not stop or change prescribed medicines based on this notice.
May lower blood sugar; monitor
Tip: Take with food; reduce dose
Tip: Take with food or water
Ginger Extract has an evidence score of 7/10 — strong evidence based on 115 indexed studies, including 11 meta-analyses. Gingerols and shogaols reduce nausea, accelerate gastric emptying, and provide systemic anti-inflammatory benefits. Representative study: PMID 37033930.
The commonly studied dose of Ginger Extract is 480-1,000 mg extract daily. The lowest cited dose that helped was 480 mg a day of steamed ginger extract, for gastric symptoms. In a cited chemotherapy-nausea trial, 250 mg and 500 mg ginger capsules did no better than placebo. Individual needs vary — start at the lower end of the range and adjust based on how you respond.
The best time to take Ginger Extract is with meals. Take it with food. Ginger (Zingiber officinale) has been used for millennia as a digestive aid.
Ginger Extract is generally well-tolerated and considered safe for most healthy adults at recommended doses. Reported side effects are uncommon and include heartburn, mouth irritation. Use caution if any of these apply to you: Gallstones (high doses may stimulate bile).
Curcumin
Probably helpsTurmeric's active compound that modulates NF-kB inflammatory pathways — supports mood, joint health, and post-exercise recovery.
Omega-3
Probably helpsEssential fatty acids critical for brain health, mood regulation, and reducing inflammation throughout the body.
Zinc
Likely helpsInvolved in 300+ enzymatic reactions — supports immune defense, testosterone production, wound healing, and sleep quality.
Vitamin D3
Probably helpsHormone-like vitamin that regulates 1,000+ genes — deficiency is widespread and linked to poor immunity, depression, and bone loss.
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Reviewed by Dr. Baher Al Hakim · Last reviewed May 2026 · evidence from 115 studies · how we score · editorial policy
This information is for educational purposes only. It is not a substitute for professional medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement or medication.
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