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Head-to-head evidence comparison — which supplement is right for you?
Bimatoprost (lashes) wins 2 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Mostly mechanism / observational
Top outcomes
Verdict
Mostly mechanism / observational
Top outcomes
Prescription topical. Bimatoprost 0.03% is applied once daily as a thin line to the skin of the UPPER eyelid margin at the lash base (not to the lower lid, and avoid getting it in the eye), using a fresh applicator per eye. Continuous use is needed to maintain results. Use under a clinician, especially if you have glaucoma or take prostaglandin eye drops. There is no oral or systemic use. This library does not provide an ingestion protocol.
evening
Bimatoprost 0.03% solution (Latisse) with single-use applicators, under a clinician
Topical cosmetic only. Leave-on glycolic acid is used at roughly 5-15% in lotions/serums (often at low pH), applied to clean skin a few nights per week and building as tolerated; professional peels (20-70%) are applied in-office at intervals. There is no oral, injectable, or systemic dose — it is not ingested. Pair with daily sunscreen. This library does not provide an ingestion protocol.
evening
Leave-on lotion or serum (≈5-15% glycolic acid)
Throughout
8-16 weeks
2-6 months after stopping
Weeks to months
Throughout
8-12 weeks
8-16 weeks
First weeks
Long-term safety and efficacy of bimatoprost solution 0.03% application to the eyelid margin for the treatment of idiopathic and chemotherapy-induced eyelash hypotrichosis: a randomized controlled trial.
Br J Dermatol (2015) · Rct
1-year double-masked RCT: composite primary endpoint (Global Eyelash Assessment + satisfaction) met for bimatoprost vs vehicle in idiopathic (40.2% vs 6.8%) and post-chemotherapy (37.5% vs 18.2%) hypotrichosis
Bimatoprost for eyelash growth in Japanese subjects: two multicenter controlled studies.
Aesthetic Plast Surg (2014) · Rct · n=209
Two double-masked vehicle-controlled RCTs (n=209: 173 idiopathic, 36 chemotherapy-induced) in Japanese subjects
The efficacy of topical prostaglandin analogs for hair loss: A systematic review and meta-analysis.
Front Med (Lausanne) (2023) · Meta analysis
Meta-analysis of six placebo-controlled RCTs of topical prostaglandin analogs (incl. bimatoprost) for hair growth (lashes, brows, scalp)
A double-blind randomized clinical trial on the effectiveness of a daily glycolic acid 5% formulation in the treatment of photoaging.
Dermatol Surg (1998) · Rct · n=75
75 volunteers applied 5% unneutralized glycolic acid cream or placebo to face and neck daily for 3 months (double-blind, randomized, placebo-controlled)
Clinical improvement of photoaged skin with 50% glycolic acid. A double-blind vehicle-controlled study.
Dermatol Surg (1996) · Rct · n=41
41 volunteers received a 50% glycolic acid peel vs vehicle weekly for 4 weeks (in-office peel strength)
Mode of action of glycolic acid on human stratum corneum: ultrastructural and functional evaluation of the epidermal barrier.
Arch Dermatol Res (1997) · Open label
Electron-microscopy study of human skin after 3 weeks of 4% glycolic acid twice daily
Bimatoprost (lashes) has a higher evidence score (8/10 vs 6/10) and wins in 2 of 3 categories.
No known interactions between Bimatoprost (lashes) and Glycolic Acid have been documented in our database. However, always consult a healthcare provider before combining supplements.