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Testosterone, prostate, and libido. The supplement evidence here is uneven — some compounds have decades of trials, others ride on testimonials and small pilots.
Top picks: Ashwagandha, Chromium, and Fenugreek — full evidence and dosage details below.
Pick the outcome you actually care about for the most relevant supplements.
Ranked by how many of this area's outcomes each supplement shows pooled benefit on. Click a row for the per-outcome breakdown.
Tribulus terrestris for management of patients with erectile dysfunction: a systematic review and meta-analysis of randomized trials
2026 · International journal of impotence research · meta-analysis
A comparative evaluation of on-demand phosphodiesterase-5 inhibitor efficacy in erectile dysfunction treatment: a systematic review and network meta-analysis of double-blind, placebo-controlled, randomized trials
2026 · The journal of sexual medicine · meta-analysis
Pomegranate in Cancer Therapy: A Review of Anticancer Potential, Mechanisms and Clinical Challenges in Breast, Colon and Prostate Cancers
2026 · Phytotherapy research : PTR · review
Vitamin D supplementation in infertile men: a systematic review and meta-analysis of effects on semen quality and endocrine function
2026 · PeerJ · meta-analysis
Silybum marianum-Derived Compounds in Prostate Cancer: Mechanisms of Action and Translational Potential
2026 · International journal of molecular sciences · review
Practical, evidence-tiered guides on these topics.
The popular one (saw palmetto) mostly fails in rigorous trials; beta-sitosterol is the better bet.
CoQ10, zinc, selenium, carnitine modestly help sperm parameters — but live-birth evidence is weak.
Mostly hype unless you’re deficient — what has modest evidence vs what doesn’t, and when to see a doctor.
Pick your specific goals and we'll match supplements based on the evidence for each one.
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