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Topical use. Adapalene 0.1% (OTC) or 0.3% (prescription) gel/cream is applied as a thin layer to the whole affected area once daily, usually at night, starting every other day and building to nightly as tolerated. Full benefit takes ~8-12 weeks. There is no oral or systemic dose — it is not ingested. It is most effective combined with benzoyl peroxide. This library does not provide an ingestion protocol.

Evening

Adapalene 0.1% gel/cream (OTC), applied nightly to the whole area

Topical cosmetic only. Ceramide-containing moisturizers are applied liberally to clean skin once or twice daily (and after bathing, to damp skin, to lock in water). There is no oral, injectable, or systemic dose in this context — it is not ingested. This library does not provide an ingestion protocol.

Any time

Ceramide-containing cream or lotion (with cholesterol and fatty acids)

• For topical (skin) use only — not for ingestion, not for injection
• Pregnancy and breastfeeding — retinoids are generally avoided as a precaution
• Known allergy/sensitivity to adapalene or formulation excipients

• Other irritating actives (other retinoids, AHAs/BHAs)
• Benzoyl peroxide

• For topical (skin) use only — not for ingestion
• Known allergy or sensitivity to formulation ingredients

• Other leave-on actives