Compare Supplements

180 mg orally once daily, with or without food, under a clinician. Available alone (Nexletol) or co-formulated with ezetimibe 10 mg (Nexlizet). A prescription drug — dosing is set by a prescriber.

Any time

Oral tablet (bempedoic acid 180 mg)

Standard approved dosing is 140 mg subcutaneously every 2 weeks OR 420 mg subcutaneously once monthly, under a clinician. A prescription drug; this is informational, not a recommendation.

Any time

Subcutaneous prefilled autoinjector (evolocumab)

• Concurrent simvastatin >20 mg or pravastatin >40 mg (bempedoic acid raises their levels)
• Active gout flare without management
• History of tendon rupture related to similar agents

• Simvastatin / pravastatin
• Corticosteroids / fluoroquinolones

• Prior serious hypersensitivity reaction to evolocumab
• Use only under clinician direction as part of a lipid-management plan

• Statins
• Ezetimibe