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Cbd5.8

CBD

Limited safety

Evidence

Evidence Score5.8/10

Studies: 15

Meta-analyses: 5

Dosage & timing

Dosage:

OTC wellness: 10-50mg/day (some anxiety studies used higher acute doses ~300mg); take with a fat-containing meal (increases absorption several-fold). Prescription Epidiolex for epilepsy is dosed by body weight under medical supervision.

Best Time:

With meals · with food

Take with food

Form:

CBD oil/tincture (third-party tested for potency and purity)

What you'll notice

🧘 Reduced anxiety45%

Acute-4 weeks

💢 Pain relief45%

1-8 weeks

⚡ Seizure reduction (prescription)50%

Weeks

Safety

Limited safety

Contraindications:

Concurrent use of CYP3A4/CYP2C19-metabolized drugs (incl. clobazam, some statins, blood thinners) without medical supervision
Liver disease or elevated liver enzymes
Pregnancy and breastfeeding

Drug Interactions:

Clobazam and some antiepileptics
Blood thinners (warfarin)
Valproate

Side Effects:

Somnolence/sedation, fatigueDiarrhea / GI upsetAppetite/weight changes

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