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Cof5.0

Cocoa Flavanols

High safety

Evidence

Evidence Score5/10

Studies: 5

Meta-analyses: 2

Dosage & timing

Dosage:

500-750mg cocoa flavanols daily (COSMOS used 500mg; endothelial benefit peaked near 710mg)

Best Time:

Any time

Can take on empty stomach

Form:

Standardized cocoa flavanol extract (epicatechin-standardized)

What you'll notice

📉 Modest blood-pressure reduction45%

2-8 weeks

🩸 Improved endothelial function50%

Acute to 8 weeks

❤️ Possible CV-mortality signal0%

Years

Safety

High safety

Contraindications:

Caffeine sensitivity (cocoa contains some caffeine/theobromine)
Caution with the added sugar/fat if consumed as chocolate

Drug Interactions:

Antihypertensive drugs
Stimulant sensitivity

Side Effects:

Mild GI complaints / nausea

Works well with

Epicatechin

complementary

Omega-3

complementary

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