Compare Supplements

Side-by-side comparison of 2 supplements

Cof5.0

Cocoa Flavanols

High safety

Col9.0

Collagen

High safety

Evidence

Evidence Score5/10

Studies: 5

Meta-analyses: 2

Evidence Score9/10

Studies: 42

Meta-analyses: 12

Dosage & timing

Dosage:

500-750mg cocoa flavanols daily (COSMOS used 500mg; endothelial benefit peaked near 710mg)

Best Time:

Any time

Can take on empty stomach

Form:

Standardized cocoa flavanol extract (epicatechin-standardized)

Dosage:

15g

Best Time:

Any time · with food (preferred)

Can take on empty stomach

Form:

Hydrolyzed collagen peptides (powder)

What you'll notice

📉 Modest blood-pressure reduction45%

2-8 weeks

🩸 Improved endothelial function50%

Acute to 8 weeks

❤️ Possible CV-mortality signal0%

Years

✨ Improved Skin Elasticity70%

8-12 weeks

🦵 Reduced Joint Pain65%

8-12 weeks

💅 Stronger Nails55%

12 weeks

Safety

High safety

Contraindications:

Caffeine sensitivity (cocoa contains some caffeine/theobromine)
Caution with the added sugar/fat if consumed as chocolate

Drug Interactions:

Antihypertensive drugs
Stimulant sensitivity

Side Effects:

Mild GI complaints / nausea

High safety

Contraindications:

Allergy to source (fish, shellfish, eggs, beef)
Phenylketonuria (some products contain phenylalanine)

Drug Interactions:

No significant interactions known

Side Effects:

Feeling of fullnessDigestive discomfortBad taste (some products)

Works well with

complementary

complementary

enhances

complementary

complementary

How they work together

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