Compare Supplements

Approved breast-cancer dose is 25 mg once daily with food. Off-label use in men typically uses lower or intermittent dosing (e.g. 12.5-25 mg every other day to a few times weekly) under a clinician, titrated to estradiol and testosterone with bone monitoring. A prescription drug; not an approved men's-health regimen.

With meals · with food

Oral tablet (exemestane 25 mg)

• Premenopausal women / pregnancy (teratogenic; approved only postmenopausal)
• Pre-existing osteoporosis or high fracture risk (estrogen suppression worsens bone)
• Hypersensitivity to exemestane

• Estrogen-containing therapies
• Strong CYP3A4 inducers (e.g. rifampicin)
• Bisphosphonates / bone agents