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Ezetimibe (Zetia)

Evidence Score4.4/10

Studies: 7

Meta-analyses: 1

Dosage:

10 mg once daily, with or without food, alone or added to a statin — under a clinician. A prescription drug; not a self-directed supplement regimen.

Best Time:

Any time

Can take on empty stomach

Form:

Oral tablet (ezetimibe 10 mg)

📉 LDL-C reductionpositive

2–4 weeks

❤️ Cardiovascular event reduction (with statin)positive

Months to years

✅ Very well toleratedpositive

Throughout use

Moderate safety

Contraindications:

Active liver disease or unexplained persistent transaminase elevations (when combined with a statin)
Pregnancy and breastfeeding (especially in combination with a statin)
Known hypersensitivity to ezetimibe

Drug Interactions:

Side Effects:

Myalgia (muscle aches)Elevated liver enzymesDiarrhea / abdominal discomfort

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