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Kis3.0

Kisspeptin

Limited safety

Evidence

Evidence Score3/10

Studies: 14

Meta-analyses: 0

Dosage & timing

Dosage:

No consumer dose — investigational, used only in supervised research/clinical protocols. Trials used weight-based dosing (e.g. kisspeptin-54 6.4-12.8 nmol/kg subcutaneous as a single IVF trigger; kisspeptin-54 1 nmol/kg/h IV infusion in brain-processing studies).

Best Time:

Any time

Can take on empty stomach

Form:

Kisspeptin-54 (KP-54)

What you'll notice

📈 Acute LH/FSH and testosterone risepositive

Within hours of a dose

🥚 IVF oocyte-maturation trigger (supervised trials)positive

36 h to oocyte retrieval

❤️ Modulated sexual/emotional brain responsepositive

During/after infusion

Safety

Limited safety

Contraindications:

Not for self-administration — investigational research peptide
Pregnancy/breastfeeding (outside its supervised reproductive use)
Known hypersensitivity to the peptide or formulation excipients

Drug Interactions:

Reproductive-hormone therapies (GnRH agonists/antagonists, hCG, gonadotropins)
Sex-steroid therapies (testosterone, estrogens, oral contraceptives)

Side Effects:

Well-tolerated in supervised trials (no serious adverse events reported)Tachyphylaxis (loss of LH response) with repeated dosingInjection-site reactions

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