Compare Supplements

Side-by-side comparison of 2 supplements

Lir7.5

Liraglutide

Limited safety

B17.5

Thiamine

High safety

Evidence

Evidence Score7.5/10

Studies: 12

Meta-analyses: 3

Evidence Score7.5/10

Studies: 37

Meta-analyses: 8

Dosage & timing

Dosage:

Prescription-only, clinician-titrated, subcutaneous once daily. Diabetes (Victoza): escalate 0.6 → 1.2 → 1.8 mg/day. Weight management (Saxenda): escalate weekly to 3.0 mg/day. DO NOT self-dose.

Best Time:

Any time

Can take on empty stomach

Form:

Subcutaneous once-daily injection (Victoza for diabetes, Saxenda for weight)

Dosage:

300mg

Best Time:

Morning · with food (preferred)

Take with food

Form:

Benfotiamine (fat-soluble, higher bioavailability)

What you'll notice

🩸 Improved glycemic controlpositive

Weeks to months

⚖️ Moderate weight losspositive

Months (titrated over weeks)

❤️ Reduced cardiovascular eventspositive

Months to years

⚡ Energy Productionpositive

2-4 weeks

🧠 Nerve Supportpositive

4-8 weeks

🦶 Neuropathy Relief (Benfotiamine)positive

4-12 weeks

Safety

Limited safety

Contraindications:

Personal or family history of medullary thyroid carcinoma (MTC)
Multiple Endocrine Neoplasia syndrome type 2 (MEN2)
Prior serious hypersensitivity to liraglutide or any GLP-1 receptor agonist

Drug Interactions:

Insulin and sulfonylureas
Oral medications (general)
Other GLP-1 receptor agonists

Side Effects:

NauseaVomiting / diarrhea / constipationGallbladder disease (cholelithiasis / cholecystitis)

High safety

Contraindications:

Known allergy or hypersensitivity to Thiamine or related compounds

Drug Interactions:

Loop diuretics (furosemide)
Digoxin

Side Effects:

Allergic reaction (rare, usually with IV administration)Mild GI upset

Works well with

No synergies listed

Alpha-Lipoic Acid

complementary

How they work together

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