Compare Supplements

A prescription drug for a rare growth disorder, not a performance supplement — this library does NOT provide an off-label dosing protocol. In the approved indication, mecasermin is dosed by a pediatric endocrinologist, started low (e.g. ~40 µg/kg) and titrated up to ~120 µg/kg subcutaneously twice daily, ALWAYS given shortly before or after a meal/snack to prevent hypoglycemia. There is no validated dose for muscle, performance, or anti-aging use because no such trial exists.

With meals · with food

Prescription rhIGF-1 injection (Increlex) — approved-indication use only

• Active or suspected cancer, or a history of malignancy — IGF-1 is mitogenic and a theoretical tumor-promotion risk
• Closed epiphyses / completed growth when used for the growth indication
• Intracranial hypertension or unexplained severe headaches

• Insulin and other glucose-lowering drugs
• Growth hormone / other anabolic agents
• Corticosteroids / pharmacologic glucocorticoids