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Mbl3.0

Methylene Blue

Limited safety

Evidence

Evidence Score3/10

Studies: 5

Meta-analyses: 0

Dosage & timing

Dosage:

No validated longevity dose. Nootropic use is LOW-dose (research used roughly 0.5–4 mg/kg in studies; biohacker oral use is often ~10–25 mg), USP-grade only. Higher doses become pro-oxidant and risk toxicity. Off-label/research use, not an approved regimen.

Best Time:

Any time

Can take on empty stomach

Form:

USP/pharmaceutical-grade low-dose oral

What you'll notice

🧠 Modest cognitive/memory effectpositive

Acute (hours)

🔋 Mitochondrial supportpositive

Acute

✨ Skin/anti-aging (preclinical)positive

Unknown in humans

Safety

Limited safety

Contraindications:

Use with SSRIs/SNRIs/MAOIs or other serotonergic drugs (serotonin syndrome)
G6PD deficiency (hemolysis)
Pregnancy / breastfeeding

Drug Interactions:

Serotonergic drugs (SSRIs, SNRIs, MAOIs, triptans)
Drugs causing oxidative stress in G6PD deficiency

Side Effects:

Blue/green urine and oral stainingNausea / headacheSerotonin syndrome (with serotonergic drugs)

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