Compare Supplements

Topical cosmetic only. Niacinamide is typically formulated at 2-5% in leave-on serums, creams, or gels and applied to clean skin once or twice daily (AM and/or PM). It layers well under sunscreen and with most other actives. There is no oral, injectable, or systemic dose in this cosmetic context — it is not ingested here. This library does not provide an ingestion protocol.

Any time

Leave-on topical serum or cream (2-5% niacinamide)

Topical cosmetic only. L-ascorbic acid serums are typically 10-20% (often near pH 3 for absorption); stable derivatives are used at varying percentages. Apply a few drops to clean, dry skin, usually in the morning under sunscreen (its antioxidant action complements SPF). There is no oral, injectable, or systemic dose in this cosmetic context. This library does not provide an ingestion protocol.

Morning

Leave-on topical serum (10-20% L-ascorbic acid) or a stable vitamin C derivative

• For topical (skin) use only — not for ingestion, not for injection (in this cosmetic context)
• Known allergy or sensitivity to niacinamide or formulation excipients
• Application to broken, irritated, or compromised skin until healed

• Pure ascorbic acid (vitamin C) at low pH
• Strong leave-on exfoliating actives (AHAs/BHAs, retinoids)

• For topical (skin) use only — not for ingestion, not for injection (in this cosmetic context)
• Known allergy or sensitivity to the formulation
• Application to broken, irritated, or compromised skin until healed

• Strong leave-on actives (retinoids, AHAs/BHAs, benzoyl peroxide)
• Niacinamide