Compare Supplements

Side-by-side comparison of 2 supplements

B26.5

Riboflavin

High safety

Ter7.0

Teriparatide

Limited safety

Evidence

Likely helps

Evidence Score6.5/10

Studies: 40

Meta-analyses: 12

Mostly mechanism / observational

Evidence Score7/10

Studies: 28

Meta-analyses: 3

Dosage & timing

Dosage:

400mg

Best Time:

Morning · with food

Take with food

Form:

Riboflavin or Riboflavin-5-Phosphate (R-5-P)

Dosage:

20 micrograms once daily by subcutaneous injection (the approved osteoporosis dose; PRESCRIPTION ONLY)

Best Time:

Any time

Can take on empty stomach

Form:

Subcutaneous injection (prefilled pen)

What you'll notice

🧠 Migraine Preventionpositive

3 months

⚡ Energy Supportpositive

2-4 weeks

💛 Bright Yellow Urinetrade-off

Immediate

🦴 Reduced vertebral fracturespositive

Over ~18-24 months of daily use

🛡️ Reduced nonvertebral fragility fracturespositive

Over ~18-24 months

📊 Bone-density gainspositive

Detectable by ~3 months

Safety

High safety

Contraindications:

Known allergy or hypersensitivity to Riboflavin or related compounds

Drug Interactions:

Tricyclic antidepressants
Phenobarbital
Probenecid

Side Effects:

Yellow-orange urine

Limited safety

Contraindications:

Conditions with baseline-increased osteosarcoma risk: Paget's disease of bone, unexplained elevated alkaline phosphatase, prior skeletal radiation therapy, open epiphyses (children/young adults with growth plates not yet closed)
Pre-existing hypercalcemia or hyperparathyroidism
Active bone metastases or skeletal malignancy

Drug Interactions:

Digoxin
Calcium / vitamin D supplements

Side Effects:

Hypercalcemia (transient)Orthostatic hypotension / dizzinessLeg cramps

Works well with

CoQ10

complementary

Feverfew

complementary

No synergies listed

How they work together

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