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Ros4.5

Rosuvastatin (Crestor)

Moderate safety

Evidence

Evidence Score4.5/10

Studies: 6

Meta-analyses: 2

Dosage & timing

Dosage:

5–20 mg once daily (up to 40 mg in selected high-risk patients), titrated to LDL/ApoB targets — under a clinician. A prescription drug; not a self-directed supplement regimen.

Best Time:

Any time

Can take on empty stomach

Form:

Oral tablet (rosuvastatin 5–20 mg)

What you'll notice

📉 Potent LDL-C reductionpositive

2–4 weeks

❤️ Cardiovascular event & mortality reductionpositive

Months to years

🧱 Atherosclerotic plaque regressionpositive

1–2 years

Safety

Moderate safety

Contraindications:

Active liver disease or unexplained persistent transaminase elevations
Pregnancy and breastfeeding
Known hypersensitivity to rosuvastatin

Drug Interactions:

Cyclosporine
Gemfibrozil
Certain antivirals / protease inhibitors

Side Effects:

Myalgia (muscle aches)Elevated liver enzymesNew-onset type 2 diabetes

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