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Sqa4.0

Squalane (topical)

High safety

Evidence

Evidence Score4/10

Studies: 5

Meta-analyses: 0

Dosage & timing

Dosage:

Topical cosmetic only. Squalane is used pure (100% oil) or as an emollient within moisturizers, applied to clean or damp skin as needed, often as a final step to seal in hydration. There is no oral, injectable, or systemic dose — it is not ingested. This library does not provide an ingestion protocol.

Best Time:

Any time

Can take on empty stomach

Form:

Pure squalane oil or a squalane-containing moisturizer

What you'll notice

ℹ️ A moisturizing emollient — not an activeneutral

Throughout

💧 Softens skin and reduces water losspositive

1-4 weeks

✅ Exceptionally well tolerated, low comedogenicitypositive

Throughout

Safety

High safety

Contraindications:

For topical (skin) use only — not for ingestion
Known allergy or sensitivity to the formulation

Drug Interactions:

Other leave-on actives

Side Effects:

Rare local irritation or breakouts (formulation-dependent)

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