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Thymosin Alpha-1

Evidence Score5/10

Studies: 14

Meta-analyses: 9

Dosage:

Approved-label hepatitis regimen: 1.6 mg subcutaneously twice weekly (thymalfasin/Zadaxin). PRESCRIPTION DRUG abroad — not a self-dosed supplement.

Best Time:

Any time

Can take on empty stomach

Form:

Thymalfasin (Zadaxin) subcutaneous injection

🦠 Improved hepatitis B response (evidenced)positive

Months (response often accrues after end of therapy)

🧬 Immune restoration in critical illnesspositive

Days to weeks (acute care)

❓ Mixed COVID-19 resultsneutral

Acute illness

Moderate safety

Contraindications:

Not a US-approved drug or dietary supplement — only use the regulated product where licensed and under medical supervision
Immunosuppressed transplant recipients (theoretical immune-activation risk — physician-directed only)
Known hypersensitivity to thymalfasin

Drug Interactions:

Side Effects:

Injection-site reactions (redness, discomfort)Transient liver-enzyme (ALT) flareMild, self-limiting general reactions reported in trials

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