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Topical use, typically ~2-5% tranexamic acid in a serum applied to areas of melasma once or twice daily, alongside daily sunscreen. There is no oral or systemic dose in this cosmetic context — the ingested medication is a separate prescription use with clotting-risk considerations. This library does not provide an ingestion protocol.

Any time

Leave-on topical serum (≈2-5% tranexamic acid)

Topical cosmetic only. L-ascorbic acid serums are typically 10-20% (often near pH 3 for absorption); stable derivatives are used at varying percentages. Apply a few drops to clean, dry skin, usually in the morning under sunscreen (its antioxidant action complements SPF). There is no oral, injectable, or systemic dose in this cosmetic context. This library does not provide an ingestion protocol.

Morning

Leave-on topical serum (10-20% L-ascorbic acid) or a stable vitamin C derivative

• Topical use here is for skin only — do not self-medicate with oral tranexamic acid for melasma without a clinician (clotting-risk considerations)
• Known allergy or sensitivity to tranexamic acid or formulation excipients
• Application to broken, irritated, or compromised skin until healed

• Other leave-on brighteners/actives

• For topical (skin) use only — not for ingestion, not for injection (in this cosmetic context)
• Known allergy or sensitivity to the formulation
• Application to broken, irritated, or compromised skin until healed

• Strong leave-on actives (retinoids, AHAs/BHAs, benzoyl peroxide)
• Niacinamide