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Yhb5.0

Yohimbine

Limited safety

Evidence

Evidence Score5/10

Studies: 6

Meta-analyses: 2

Dosage & timing

Dosage:

Standardized yohimbine HCl ~0.2 mg/kg (roughly 5-15 mg) up to 1-2x daily; start at the lowest dose, ideally fasted for the fat-loss effect. Never combine with other stimulants.

Best Time:

Morning

Can take on empty stomach

Form:

Standardized yohimbine HCl (known dose)

What you'll notice

📉 Modest fat losspositive

3-8 weeks

💪 Improved erectile functionpositive

2-8 weeks

❤️ Raised heart rate & blood pressuretrade-off

Acute

Safety

Limited safety

Contraindications:

Hypertension or cardiovascular disease
Anxiety, panic, or other psychiatric disorders
Kidney or liver disease

Drug Interactions:

MAO inhibitors
SSRIs/SNRIs and other serotonergic/noradrenergic drugs
Stimulants (caffeine, other sympathomimetics)

Side Effects:

Increased heart rate and blood pressureAnxiety, jitteriness, insomniaHeadache, nausea, sweating

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