43 peer-reviewed studies · Evidence score: 8/10
Zhao G et al. • Reproductive biology and endocrinology : RB&E (2025)
Chromium, inositol, and Omega-3 were found to be beneficial for improving lipid profile.
Viscardi G et al. • Advances in nutrition (Bethesda, Md.) (2025)
Addressing public health concerns may promote soy foods as high-quality plant protein sources with low environmental impact and cost, particularly benefiting postmenopausal women and aligning with ...
Zuo X et al. • Nutrients (2023)
This study has been registered on PROSPERO (registration number: CRD42022360504).
Luan H et al. • PeerJ (2025)
More trials should be conducted in the future to validate our findings.
Akhlaghi M et al. • Critical reviews in food science and nutrition (2020)
Soy isoflavones prevent osteoporosis-related bone loss in any weight status or treatment duration.
Reed KE et al. • Reproductive toxicology (Elmsford, N.Y.) (2021)
Sub-analysis of the data according to isoflavone dose and study duration also showed no effect.
Pitsouni E et al. • European journal of obstetrics, gynecology, and reproductive biology (2018)
Dyspareunia and/or vaginal dryness were assessed in 72% of the articles, while the FSD and orgasm in 45% and 28% of articles, respectively.
Chakravarti B et al. • Phytotherapy research : PTR (2024)
Therefore, caution should be exercised when considering the intake of dietary isoflavones in female hormone-dependent cancer patients, particularly in the form of supplements.
Wang Y et al. • Journal of the science of food and agriculture (2021)
However, high intake of isoflavones may not be associated with the incidence of GC. © 2021 Society of Chemical Industry.
Inpan R et al. • Archives of osteoporosis (2024)
This systematic review and meta-analysis highlight the potential of isoflavone interventions to rectify imbalances in bone remodeling, enhance bone mineral homeostasis, and optimize hormones regulating bone metabolism in postmenopausal women.
Inpan R et al. • Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2024)
This systematic review and meta-analysis suggests that isoflavone interventions, especially those containing genistein of at least 50 mg/day, can effectively enhance BMD in postmenopausal women.
Fan ZK et al. • The British journal of nutrition (2022)
The present results indicate that dietary intakes of fruits and vegetables abundant five flavonoid subclasses, namely anthocyanins, proanthocyanidins, flavonols, flavones and isoflavones, are associated with a lower risk of CHD.
Lambert MNT et al. • Nutrients (2020)
Red clover isoflavone supplementation attenuated bone mineral density loss in early postmenopausal women.
Qin Y et al. • The Cochrane database of systematic reviews (2013)
We found no evidence for effects of isoflavones on patient-important outcomes or lowering of cholesterol levels in people with hypercholesterolaemia.
Leach MJ et al. • The Cochrane database of systematic reviews (2012)
There is currently insufficient evidence to support the use of black cohosh for menopausal symptoms.
van Die MD et al. • JNCI cancer spectrum (2024)
Soy, enterolactone, and green tea demonstrated significant risk reductions in outcomes following breast cancer.
Gençtürk N et al. • Explore (New York, N.Y.) (2024)
According to the results of the analysis, soy isoflavones had no effect on menopausal symptoms (vasomotor, psychosocial, physical, sexual, and urogenital complaints) and quality of life in climacteric women but did reduce the level of depression.
Prokopidis K et al. • The British journal of nutrition (2023)
These data support that whey and soy protein supplementation elicit anti-inflammatory effects by reducing circulating IL-6 and TNF-α levels, respectively.
Yang S et al. • Advances in nutrition (Bethesda, Md.) (2023)
Isoflavone consumption resulted in a significant reduction in triacylglycerol (TG) concentrations (-12.50 mg/dL; 95% CI: -23.09, -1.91) and a modest increase in high-density lipoprotein cholesterol...
Błaszczuk A et al. • Nutrients (2022)
This meta-analysis provides evidence that consuming flaxseed, soy and red clover can have a beneficial effect on lipids in postmenopausal women and suggest a favorable effect in preventing cardiovascular diseases.