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Saf7.5
Saffron – Forschung
Hilft wahrscheinlich
188 begutachtete Studien
Was die Evidenz sagt
Hilft wahrscheinlich
Saffron scheint in 6 von 7 Studien mit messbaren Effekten zu helfen — die Evidenz tendiert klar ins Positive.
Die meiste Evidenz stammt aus hochwertigen Meta-Analysen und randomisierten Studien, veröffentlicht 2004–2026 mit einer typischen Studiengröße von 70 Teilnehmenden.
Basierend auf 188 Studien · 35 Meta-Analysen · 97 RCTs · 29,830 Teilnehmende insgesamt
Konfidenz
Hohe Konfidenz
Was die Studien gefunden haben
6geholfen1unklar· 181 weitere ohne bewertete Effektdaten
Neuroprotection & brain agingCrocin und Safranal fördern Entspannung und Einschlafen · 2-4 Wochen
Überwiegend Mechanismus / Beobachtung19 Studien
Anxiety & stressModerate Verbesserung des Schlafs · 4 Wochen
Hilft wahrscheinlich18 Studien
Glucose & metabolic
Überwiegend Mechanismus / Beobachtung13 Studien
Inflammation
Überwiegend Mechanismus / Beobachtung13 Studien
Cognitive functionNeuroprotective crocin supports learning and memory · 4-8 weeks
Überwiegend Mechanismus / Beobachtung12 Studien
Safety profile
Überwiegend Mechanismus / Beobachtung10 Studien
Sleep & insomniaKann die reproduktive Gesundheit und Fertilitätsmarker unterstützen · 4-12 Wochen · Crocin zeigt neuroprotektive Wirkungen in Studien zum kognitiven Altern · 8-12 Wochen
Vision & eye healthKann helfen, Menstruationsbeschwerden und PMS-Symptome zu reduzieren · 1-3 Zyklen
Überwiegend Mechanismus / Beobachtung7 Studien
Weight management
Überwiegend Mechanismus / Beobachtung5 Studien
Focus & attentionImproves attention and processing speed in clinical trials · 4-8 weeks
Überwiegend Mechanismus / Beobachtung4 Studien
In Zahlen
Aus 48 Studien mit messbaren Effekten gezogen
Wahrscheinlich echte Effekte
67%
über Studien hinweg
Untersuchte Personen
30k
typische Studie: 70 Personen
Stärkste Designs
132
35 gepoolt, 97 randomisiert
Zeigte Nutzen
86%
6/7 Studien
Wie lange Studien liefen
1–4 Wochen
1
1–3 Monate
3
3+ Monate
1
Untersuchte Populationen
Various patient populations3
Adults with mild-to-moderate depression2
General population2
ADHD patients1
Aktives Forschungsgebiet
104 Studien in den letzten 5 Jahren · Neueste Meta-Analyse: 2026
200420152026
1Meta-Analysen=17,437 · very large study2025
Einfach gesagt: This extensive systematic review and NMA of nutraceuticals for treating depressive disorders indicated a number of nutraceuticals that could offer benefits, either as adjuncts or monotherapies.
Cheng YC et al. · Psychological medicine (2025)
Adjunctive nutraceuticals consistently showed better efficacy than antidepressants (ADT) alone in outcomes including SMD, remission, and response.
This extensive systematic review and NMA of nutraceuticals for treating depressive disorders indicated a number of nutraceuticals that could offer benefits, either as adjuncts or monotherapies.
Einfach gesagt: Dietary polyphenols may improve DAS28, reduce C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR), and improve oxidative stress, etc.
Long Z et al. · Frontiers in immunology (2023)
Dietary polyphenols may improve DAS28, reduce C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR), and improve oxidative stress, etc.
However, more RCTs are needed to verify or modify the efficacy and safety of dietary polyphenols.
3ADHD symptomsSystematische Übersichtn=118 · medium study2024
Einfach gesagt: The results manifested an efficient role of saffron as either an adjuvant therapy to MPH or a single therapy against ADHD, without significant safety issues.
Seyedi-Sahebari S et al. · Journal of attention disorders (2024)
5Insomnia improvementMeta-Analysen=431 · medium study2022
Einfach gesagt: This non-pharmacological intervention may reduce the chance of adults with insomnia taking sedative-hypnotic medication, thus reducing dependency and withdrawal symptoms.
Munirah MP et al. · International journal of environmental research and public health (2022)
Eight articles were included, involving 431 participants.
Although there is limited evidence of a very low- to moderate-quality, Crocus sativus may benefit people with insomnia.
This non-pharmacological intervention may reduce the chance of adults with insomnia taking sedative-hypnotic medication, thus reducing dependency and withdrawal symptoms.
Einfach gesagt: This review concluded that C. sativus can improve the symptoms of several female reproductive system disorders, which is particularly due to the presence of phytochemical ingredients, such as crocin, crocetin, and safranal.
Hasheminasab FS et al. · Phytotherapy research : PTR (2024)
These studies confirmed the efficacy of C. sativus or its main phytochemical ingredients in several aspects of the female reproductive system, including regulation of sex hormones, folliculogenesis, ovulation, and protection of the ovary and uterus against several oxidative stress.
Several retrieved studies indicated that this herb also can alleviate the symptoms of patients suffering from dysmenorrhea, premenstrual syndrome, menopause, polycystic ovary disease (PCOD), and sexual dysfunction.
Furthermore, it is a promising candidate for future studies or even trials regarding ovarian and cervical cancers.
Einfach gesagt: Only ginger and black cumin reported a significant improvement in glycated hemoglobin, and only cinnamon and ginger showed a significant decrease in insulin.
Garza MC et al. · Nutrients (2024)
Our results showed that cinnamon, turmeric, ginger, black cumin, and saffron significantly improved the fasting glucose levels in T2DM subjects.
The most significant decreases in fasting glucose were achieved after supplementation with black cumin, followed by cinnamon and ginger, which achieved a decrease of between 27 and 17 mg/dL.
Only ginger and black cumin reported a significant improvement in glycated hemoglobin, and only cinnamon and ginger showed a significant decrease in insulin.