15 peer-reviewed studies · Evidence score: 6.2/10
Ulbricht C et al. • Journal of dietary supplements (2010)
A comprehensive evidence-based review of spearmint covering pharmacology, interactions, adverse effects, and dosing, synthesizing available scientific literature and expert opinion.
Grant P et al. • Phytotherapy research : PTR (2010)
Free and total testosterone levels were significantly reduced over the 30 day period in the spearmint tea group (p < 0.05), and LH and FSH also increased (p < 0.05).
Herrlinger KA et al. • Journal of alternative and complementary medicine (New York, N.Y.) (2018)
Supplementation with spearmint extract significantly improved working memory in men and women with age-associated memory impairment compared to placebo.
Falcone PH et al. • Nutrition research (New York, N.Y.) (2019)
Spearmint extract supplementation significantly improved sustained attention and accuracy in a cognitively demanding task compared to placebo in healthy adults.
Falcone PH et al. • Journal of the International Society of Sports Nutrition (2018)
Spearmint extract significantly improved reactive agility compared to placebo in a randomized controlled trial, supporting its nootropic potential for sports performance applications.
Lasrado JA et al. • Regulatory toxicology and pharmacology : RTP (2017)
Ingestion of both 600 and 900 mg/day of dried aqueous spearmint extract for 90 days had no effect on plasma levels of follicular stimulating hormone, luteinizing hormone, thyroid stimulating hormone, or other safety parameters.
Khorasani F et al. • Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology (2020)
Herbal medicines such as matricaria chamomilla, elettaria cardamomum, pomegranate and spearmint syrup, lemon provide safe and effective medical alternatives for treating pregnant women with mild to moderate nausea and vomiting of pregnancy.
Akdoğan M et al. • Phytotherapy research : PTR (2007)
After treatment with spearmint teas, there was a significant decrease in free testosterone and increase in luteinizing hormone, follicle-stimulating hormone and estradiol.
Connelly AE et al. • Journal of medicinal food (2014)
High-rosmarinic acid spearmint tea significantly reduced knee osteoarthritis pain and stiffness compared to commercially available spearmint tea over 16 weeks.
Saeidi S et al. • Journal of cosmetic dermatology (2024)
Topical B. integerrima root extract combined with spearmint essential oil significantly reduced acne lesion count and mGAGS score, with effects comparable to topical clindamycin.
Ostfeld I et al. • Journal of special operations medicine : a peer reviewed journal for SOF medical professionals (2018)
Spearmint extract containing rosmarinic acid attenuated declines in executive functioning and physical performance following a fatiguing tactical operation.
Hunt R et al. • Anesthesia and analgesia (2013)
Aromatherapy with spearmint and other essential oils significantly reduced postoperative nausea compared to a saline control in this randomized trial.
Kennedy D et al. • Nutrients (2018)
Volatile terpenes from Mentha species interact with central nervous system receptors and demonstrate in vitro cholinergic and GABAergic activity relevant to cognitive and mood enhancement.
Kiberd MB et al. • BMC complementary and alternative medicine (2016)
Aromatherapy with essential oils including spearmint demonstrated a trend toward reducing postoperative nausea and vomiting in pediatric surgical patients in this pilot RCT.
de Souza Silva JE et al. • Archives of gerontology and geriatrics (2014)
Spearmint and other mint-family herbs are among the most commonly used herbal medicines by elderly patients, with a generally favorable safety profile but potential for interactions with conventional medications.