26 peer-reviewed studies · Evidence score: 6/10
Gagnier JJ et al. • Cochrane Database of Systematic Reviews (2016)
Salix alba (white willow bark) showed moderate evidence for short-term improvement in low back pain compared to placebo.
Gagnier JJ et al. • Cochrane Database of Systematic Reviews (2006)
Moderate evidence supports willow bark for low back pain.
Allard T et al. • Current medicinal chemistry (2013)
Strategies to minimize nephrotoxicity include (1) quality control and standardization of herbal products, (2) research on the molecular modes of action to better understand pathophysiological mechanisms of herbal products as well as (3) clinical trials to demonstrate efficacy and safety.
Shara M et al. • Phytotherapy research : PTR (2015)
The primary cause for concern may relate to allergic reactions in salicylate-sensitive individuals.
Nyakudya TT et al. • Molecules (Basel, Switzerland) (2020)
We aim to provide the state of the current knowledge on the use of medicinal plants and their therapeutically important phytochemicals by discussing the current trends, with critical examples from recent primary references of how medicinal plants are being used in South African rural and urban communities.
Oketch-Rabah HA et al. • Planta medica (2019)
In the interest of protecting public health, the United States Pharmacopeia has included a cautionary labeling statement in the United States Pharmacopeia Salix Species monograph as follows: "Dosage forms prepared with this article should bear the following statement: 'Not for use in children, women who are pregnant or nursing, or by persons with known sensitivity to aspirin.'".Georg Thieme Verlag KG Stuttgart · New York.
Parvez MK • Current drug metabolism (2018)
Certainly, extensive work is needed to make sure that patients should take a regimen of protective and restorative therapy under an experienced healthcare professional.
Juurlink BH et al. • Nutrition journal (2014)
Hippocrates' dictum of 'Let food be your medicine and medicine your food' can now be experimentally tested and the results of such experiments will enhance the ability of nutritionists to devise specific health-promoting diets.
Taheri JB et al. • International dental journal (2011)
Herbs may be good alternatives to current treatments for oral health problems but it is clear that we need more research.
Vlachojannis JE et al. • Phytotherapy research : PTR (2009)
Further studies are required to find out if treatment of osteoarthritis and rheumatoid arthritis requires extract with higher doses than 240 mg salicin per day.
Mahdi JG et al. • Cell proliferation (2006)
The historical steps that led to the discovery of aspirin, and its antiproliferative and anticancer potential are highlighted in this review.
Nahrstedt A et al. • Wiener medizinische Wochenschrift (1946) (2007)
The single compounds or their combinations responsible for the effect remain to be elucidated.
Shrivastava R et al. • Clinical drug investigation (2006)
The remarkable efficacy of Mig-RL in not only reducing the frequency of migraine attacks but also their pain intensity and duration in this trial warrants further investigation of this therapy in a double-blind, randomised, placebo-controlled investigation involving a larger patient population.
Nieman DC et al. • Nutrition journal (2013)
Results from this randomized, double blind, placebo-controlled community trial support the use of the Instaflex™ dietary supplement in alleviating joint pain severity in middle-aged and older adults, with mitigation of difficulty performing daily activities most apparent in subjects with knee pain.
Yang F et al. • Journal of cosmetic dermatology (2024)
Our results showed that the novel emulsion containing three active ingredients could effectively improve acne, blackheads, and conspicuous facial pores.
Evans M et al. • Nutrients (2020)
Pain Bloc-R performed as well as acetaminophen in managing unresolved non-pathological pain in otherwise healthy individuals.
Chrubasik S et al. • American Journal of Medicine (2000)
Willow bark was more effective than placebo for low back pain.
Schmid B et al. • Phytotherapy Research (2001)
Willow bark reduced pain in hip and knee OA.
Risso DS et al. • Appetite (2017)
This is the first study that concurrently explores the contribution of genetics, population diversity and cultural aspects in taste perception and food consumption.
Schink A et al. • PloS one (2018)
Several promising anti-inflammatory herbal extracts were identified in this study, including extracts with previously unknown influence on key TLR signaling pathways and macrophage repolarization, serving as a basis for novel lead compound identification.