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Head-to-head evidence comparison — which supplement is right for you?
ASU wins 1 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Mostly mechanism / observational
Top outcomes
Verdict
Mostly mechanism / observational
Top outcomes
Shared outcomes (1)
Outcomes where both ASU and Rosehip have evidence — compare verdict strength side-by-side.
300mg ASU daily (standardized avocado:soybean unsaponifiables)
with-meals
Standardized ASU (300mg)
5g daily of standardized rosehip powder (the dose used in the OA trials)
with-meals
Standardized rosehip powder (GOPO-standardized)
1-3 months
1-3 months
Throughout use
3 weeks to 3 months
3-12 weeks
Throughout use
Efficacy and safety of avocado-soybean unsaponifiables for the treatment of hip and knee osteoarthritis: A systematic review and meta-analysis of randomized placebo-controlled trials.
Int J Rheum Dis (2019) · Meta analysis
A subanalysis according to the type of OA showed that ASU significantly decreased both VAS and Lequesne index in knee OA (WMD: -17.36, 95% CI: -25.91, -8.82; P < .0001 and WMD: -2.33, 95% CI: -2.88, -1.78; P < .00001, respectively) but not in hip OA.
Symptomatic efficacy of avocado-soybean unsaponifiables (ASU) in osteoarthritis (OA) patients: a meta-analysis of randomized controlled trials.
Osteoarthritis Cartilage (2008) · Meta analysis
Four trials were included, with 664 OA patients with either hip (41.4%) or knee (58.6%) OA allocated to either 300 mg ASU (336) or placebo (328).
Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis.
Br J Sports Med (2018) · Meta analysis
Of 20 supplements investigated in 69 eligible studies, avocado soybean unsaponifiables revealed statistically significant improvements on pain, but were of unclear clinical importance.
Does the hip powder of Rosa canina (rosehip) reduce pain in osteoarthritis patients?--a meta-analysis of randomized controlled trials.
Osteoarthritis Cartilage (2008) · Meta analysis · n=287
Pooled three RCTs (287 patients, median 3-month duration)
A powder made from seeds and shells of a rose-hip subspecies (Rosa canina) reduces symptoms of knee and hip osteoarthritis: a randomized, double-blind, placebo-controlled clinical trial.
Scand J Rheumatol (2005) · Crossover · n=94
94 patients, randomized double-blind placebo-controlled crossover, 5g/day for 3 months
The clinical effectiveness of rosehip powder in patients with osteoarthritis. A systematic review.
MMW Fortschr Med (2007) · Systematic review
Systematic review of two double-blind RCTs (N=100 and 112, Jadad score 5)
ASU has a higher evidence score (5.5/10 vs 5/10) and wins in 1 of 3 categories.
For joint health & mobility, Rosehip has a higher relevance score (62 vs 60).
No known interactions between ASU and Rosehip have been documented in our database. However, always consult a healthcare provider before combining supplements.