Loading…
We use essential cookies (authentication, your saved goals/stack) by default. With your permission we’ll also enable privacy-respecting analytics (Vercel Web Analytics, anonymous load-time metrics) and error-replay diagnostics (Sentry — DOM snapshots only when an error fires) so we can fix bugs faster. Learn more about cookies
Head-to-head evidence comparison — which supplement is right for you?
Beta-Sitosterol vs Rye Pollen Extract: Beta-Sitosterol has the stronger overall evidence (5 vs 4.8/10); they're alternatives for prostate health — the best pick depends on your goals. Take the 60-second quiz for a pick tailored to your goals.
Beta-Sitosterol wins 2 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Too few graded studies
Top outcomes
Verdict
Too few graded studies
Top outcomes
Shared outcomes (1)
Outcomes where both Beta-Sitosterol and Rye Pollen Extract have evidence — compare verdict strength side-by-side.
60 to 130 mg a day for BPH urinary symptoms, the doses of the two six-month placebo-controlled trials: 20 mg three times a day, and 130 mg of free beta-sitosterol once a day. Both used phytosterol extracts with beta-sitosterol as the main component, so check the label for the beta-sitosterol content. For lowering cholesterol, gram doses of plant sterols or stanols are a different product: see the Plant Sterols & Stanols entry.
Once daily or in divided doses
Phytosterol extract standardised to beta-sitosterol
2 capsules/tablets three times daily (every 8 hours), or 375-750 mg twice daily
Three divided doses per day, roughly every 8 hours, With or without food — no trial specified a meal requirement
Cernilton / Cernitin standardized rye-grass pollen extract
4-8 weeks
12-24 weeks
12-24 weeks
6-12 weeks
6-12 weeks
Efficacy and mechanisms of Xiangsha Liujunzi Decoction for gastroesophageal reflux disease: A study integrating meta-analysis, network pharmacology and molecular docking
Phytomedicine : international journal of phytotherapy and phytopharmacology (2026) · Meta analysis · n=646
Eight RCTs (n = 646) showed that XSLJZD significantly improved clinical outcomes compared with controls, demonstrating superior overall efficacy and reduced recurrence.
Efficacy and mechanism of Qianjinweijing Decoction for asthma: Integrating systematic review with meta-analysis and network pharmacology
Medicine (2025) · Meta analysis · n=1200
Systematic review and meta-analysis of 14 studies in 1,200 people with asthma, comparing Qianjinweijing Decoction, a four-herb traditional Chinese medicine, with routine drug treatment.
Treatment of gouty arthritis with traditional Chinese medicine decoction: Meta-analysis, network pharmacology analysis, and molecular docking
Medicine (2024) · Meta analysis · n=7151
TCMD could be a satisfactory complementary and alternative therapy for GA.
Therapeutic efficacy of orally administered pollen for nonallergic diseases: An umbrella review.
Phytotherapy Research (2019) · Systematic review
Reviews support grass pollen extracts for symptomatic BPH and chronic prostatitis
A pollen extract (Cernilton) in patients with inflammatory chronic prostatitis-chronic pelvic pain syndrome: a multicentre, randomised, prospective, double-blind, placebo-controlled phase 3 study
European Urology (2009) · Rct · n=139
139 men with NIH category IIIA CP/CPPS were randomised to pollen extract (n=70) or placebo (n=69), dosed as two capsules every 8 hours for 12 weeks.
A systematic review of Cernilton for the treatment of benign prostatic hyperplasia
BJU International (2000) · Systematic review · n=444
444 men were enrolled in two placebo-controlled and two comparative trials lasting 12-24 weeks; concealment of treatment allocation was unclear in all.
Beta-Sitosterol has a higher evidence score (5/10 vs 4.8/10) and wins in 2 of 3 categories.
For prostate health, Beta-Sitosterol has a higher relevance score (80 vs 78).
No documented interaction was found in the data searched. This does not establish that this exact combination is safe.
The right pick depends on your goals. Answer a few quick questions for a personalised recommendation — or dig into the full evidence on each.