Loading…
We use essential cookies (authentication, your saved goals/stack) by default. With your permission we'll also enable privacy-respecting analytics (Vercel Web Analytics, anonymous load-time metrics) and error-replay diagnostics (Sentry — DOM snapshots only when an error fires) so we can fix bugs faster. Learn more
Head-to-head evidence comparison — which supplement is right for you?
Collagen wins 2 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Likely helps
14 of 16 studies with measurable effects showed benefit.
Top outcomes
Verdict
Likely helps
6 of 6 studies with measurable effects showed benefit.
Top outcomes
160-480mg standardized extract (25% anthocyanins)
With meals
Standardized extract (25% anthocyanins or 36% anthocyanidins)
10-15g
Any time of day, With vitamin C for enhanced synthesis
Hydrolyzed collagen peptides (powder)
4-8 weeks
4-8 weeks
8-12 weeks
8-12 weeks
12 weeks
First week
Investigating the Effects of Vaccinium myrtillus Supplementation on Cardiometabolic Indices: A Systematic Review and Meta-Analysis
Phytotherapy research : PTR (2025) · Meta analysis · n=409
Mean changes and their SDs were used to calculate overall effect sizes, with the Hozo et al. method converting SEs, 95% CIs, and IQRs to SDs.
Efficacy of Bilberry and Grape Seed Extract Supplement Interventions to Improve Glucose and Cholesterol Metabolism and Blood Pressure in Different Populations-A Systematic Review of the Literature
Nutrients (2021) · Systematic review · n=20
Intervention with grape seed extract may reduce systolic and diastolic blood pressure in subjects with hypertension or metabolic syndrome.
A 12-Week-Long Intake of Bilberry Extract (Vaccinium myrtillus L.) Improved Objective Findings of Ciliary Muscle Contraction of the Eye: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Comparison Trial
Nutrients (2020) · Rct · n=109
Results showed that post-load HFC-1 values at weeks 8 and 12 were significantly improved in the SBE group than in the placebo group (p = 0.014 and 0.017, respectively).
Effects of Collagen Supplements on Skin Aging: A Systematic Review and Meta-Analysis
The American Journal of Medicine (2025) · Meta analysis · n=1474
23 RCTs with 1474 participants
Effect of collagen supplementation on knee osteoarthritis: an updated systematic review and meta-analysis of randomised controlled trials
Clinical and experimental rheumatology (2025) · Meta analysis · n=870
The meta-analysis revealed an overall significant improvement of both function [MD, -6.46 (95% CI -9.52, -3.40); I2=75%; p=0.00001] and pain scores [MD, -13.63 (95% CI -20.67, -6.58); I2=88%; p=0.00001], favouring collagen supplementation.
Impact of Collagen Peptide Supplementation in Combination with Long-Term Physical Training on Strength, Musculotendinous Remodeling, Functional Recovery, and Body Composition in Healthy Adults: A Systematic Review with Meta-analysis
Sports medicine (Auckland, N.Z.) (2024) · Meta analysis · n=768
This systematic review and meta-analysis represents the first comprehensive investigation into the effects of long-term CP supplementation combined with regular physical training on various aspects of musculoskeletal health in adults.
Based on single RCT showing improvement in critical flicker frequency after 8 weeks in VDT workers. Effect size modest and study population specific to screen workers.
Meta-analysis of 23 RCTs (n=1474) showed high-quality studies had less effect than industry-funded studies. Benefits include improved skin elasticity and hydration. Hydrolyzed collagen peptides preferred for bioavailability.
AI-estimated from published studies. Interpret as directional guidance.
Collagen has a higher evidence score (9/10 vs 7/10) and wins in 2 of 3 categories.
For healthy aging, Bilberry has a higher relevance score (85 vs 65).
No known interactions between Bilberry and Collagen have been documented in our database. However, always consult a healthcare provider before combining supplements.