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Head-to-head evidence comparison — which supplement is right for you?
L. crispatus CTV-05 vs Whey Protein: Whey Protein has the stronger overall evidence (9 vs 6/10); the best pick depends on your goals. Take the 60-second quiz for a pick tailored to your goals.
Whey Protein wins 2 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Mostly mechanism / observational
Top outcomes
Verdict
Likely helps
24 of 28 studies with measurable effects showed benefit.
Top outcomes
VAGINAL USE ONLY, by applicator: 2 x 10^9 CFU per dose. The phase 2b regimen was one dose daily for 5 days in week 1, then twice weekly for a further 10 weeks — always started after a completed course of vaginal metronidazole gel.
any
Vaginal applicator delivering L. crispatus CTV-05
20-40g per serving
Post-workout (within 2 hours), Morning, Between meals
Whey Protein Isolate
11-week dosing course, measured at 12 weeks
n/a
Days 10-28
Persisting to 24 weeks
4-8 weeks
24-48 hours post-workout
Immediate
Within hours of consumption
Randomized Trial of Lactin-V to Prevent Recurrence of Bacterial Vaginosis.
N Engl J Med (2020) · Rct · n=228
Recurrence of bacterial vaginosis by week 12: 30% (46/152) with Lactin-V vs 45% (34/76) with placebo; risk ratio 0.66 (95% CI 0.44-0.87), P=0.01
Response to Antibiotic Treatment of Bacterial Vaginosis Predicts the Effectiveness of LACTIN-V (Lactobacillus crispatus CTV-05) in the Prevention of Recurrent Disease.
Sex Transm Dis (2024) · Observational
This is a POST HOC analysis of the already-completed phase 2b LACTIN-V trial, not a new trial
Sustained effect of LACTIN-V (Lactobacillus crispatus CTV-05) on genital immunology following standard bacterial vaginosis treatment: results from a randomised, placebo-controlled trial.
Lancet Microbe (2022) · Rct · n=66
Vaginal IL-1α was significantly lower with LACTIN-V (β 0.310, SE 0.149; p=0.042)
Comparative Efficacy of Different Protein Supplements on Muscle Mass, Strength, and Physical Indices of Sarcopenia among Community-Dwelling, Hospitalized or Institutionalized Older Adults Undergoing Resistance Training: A Network Meta-Analysis of Randomized Controlled Trials
Nutrients (2024) · Meta analysis · n=5272
Treatment effects for main outcomes were expressed as standard mean difference (SMD) with 95% confidence interval (CI).
Effects of Whey Protein, Leucine, and Vitamin D Supplementation in Patients with Sarcopenia: A Systematic Review and Meta-Analysis
Nutrients (2023) · Meta analysis · n=637
However, appendicular muscle mass significantly improved in the experimental group compared to the control group.
A systematic review, meta-analysis and meta-regression of the effect of protein supplementation on resistance training-induced gains in muscle mass and strength
British Journal of Sports Medicine (2018) · Meta analysis · n=1863
Protein supplementation increases muscle mass gains
Based on multiple meta-analyses with >3000 participants. Effects require concurrent resistance training. Benefits plateau around 30-40g per serving. Isolate forms may reduce digestive issues.
AI-estimated from published studies. Interpret as directional guidance.
Whey Protein has a higher evidence score (9/10 vs 6/10) and wins in 2 of 3 categories.
No known interactions between L. crispatus CTV-05 and Whey Protein have been documented in our database. However, always consult a healthcare provider before combining supplements.
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The right pick depends on your goals. Answer a few quick questions for a personalised recommendation — or dig into the full evidence on each.