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Head-to-head evidence comparison — which supplement is right for you?
L. reuteri DSM 17938 vs Whey Protein: Whey Protein has the stronger overall evidence (9 vs 6/10); the best pick depends on your goals. Take the 60-second quiz for a pick tailored to your goals.
Whey Protein wins 2 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Mostly mechanism / observational
Top outcomes
Verdict
Likely helps
24 of 28 studies with measurable effects showed benefit.
Top outcomes
1 x 10^8 CFU daily (5 drops) for infant colic — the dose used in every positive trial
any
Oil-suspension drops standardized to DSM 17938
20-40g per serving
Post-workout (within 2 hours), Morning, Between meals
Whey Protein Isolate
1-3 weeks
n/a
1-3 days
4 weeks
4-8 weeks
24-48 hours post-workout
Immediate
Within hours of consumption
Lactobacillus reuteri to Treat Infant Colic: A Meta-analysis.
Pediatrics (2018) · Meta analysis
Day-21 adjusted mean difference in cry/fuss time: -25.4 min/day (95% CI -47.3 to -3.5)
Treating infant colic with the probiotic Lactobacillus reuteri: double blind, placebo controlled randomised trial.
BMJ (2014) · Rct · n=167
Probiotic group cried/fussed 49 minutes MORE than placebo at 1 month (95% CI 8 to 90, P=0.02)
Probiotics to prevent infantile colic.
Cochrane Database Syst Rev (2019) · Meta analysis
No difference in new cases of colic: RR 0.46 (95% CI 0.18-1.19), low certainty
Comparative Efficacy of Different Protein Supplements on Muscle Mass, Strength, and Physical Indices of Sarcopenia among Community-Dwelling, Hospitalized or Institutionalized Older Adults Undergoing Resistance Training: A Network Meta-Analysis of Randomized Controlled Trials
Nutrients (2024) · Meta analysis · n=5272
Treatment effects for main outcomes were expressed as standard mean difference (SMD) with 95% confidence interval (CI).
Effects of Whey Protein, Leucine, and Vitamin D Supplementation in Patients with Sarcopenia: A Systematic Review and Meta-Analysis
Nutrients (2023) · Meta analysis · n=637
However, appendicular muscle mass significantly improved in the experimental group compared to the control group.
A systematic review, meta-analysis and meta-regression of the effect of protein supplementation on resistance training-induced gains in muscle mass and strength
British Journal of Sports Medicine (2018) · Meta analysis · n=1863
Protein supplementation increases muscle mass gains
Based on multiple meta-analyses with >3000 participants. Effects require concurrent resistance training. Benefits plateau around 30-40g per serving. Isolate forms may reduce digestive issues.
AI-estimated from published studies. Interpret as directional guidance.
Whey Protein has a higher evidence score (9/10 vs 6/10) and wins in 2 of 3 categories.
No known interactions between L. reuteri DSM 17938 and Whey Protein have been documented in our database. However, always consult a healthcare provider before combining supplements.
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The honest tier list — proven staples vs situational vs mostly marketing. The hub the other guides feed into.
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The transition years (40s): cycle changes, mood, sleep, brain fog — foundations, vitex, and starting muscle work early.
The right pick depends on your goals. Answer a few quick questions for a personalised recommendation — or dig into the full evidence on each.