Head-to-head evidence comparison — which supplement is right for you?
Potassium and Tribulus are closely matched across evidence, studies, and safety.
99-500mg daily from supplements (food provides more)
With food to reduce GI upset, Spread throughout day, During/after exercise for athletes
Potassium Citrate or Potassium Gluconate
250-750mg daily (standardized to 45-60% saponins)
With meals, Morning or divided doses
Extract standardized to 45-60% saponins (protodioscin)
2-4 weeks
1-2 weeks
Long-term
With excess or kidney issues
2-4 weeks
4-8 weeks
N/A
The effects of antidepressants on cardiometabolic and other physiological parameters: a systematic review and network meta-analysis
Lancet (London, England) (2025) · Meta analysis · n=534
We found strong evidence that antidepressants differ markedly in their physiological effects, particularly for cardiometabolic parameters.
Spironolactone in patients on chronic haemodialysis at high risk of adverse cardiovascular outcomes (ALCHEMIST): a multicentre, double-blind, randomised, placebo-controlled trial and updated meta-analysis
Lancet (London, England) (2025) · Meta analysis · n=1442
In patients with kidney failure on haemodialysis and with high risk of adverse cardiovascular outcomes, spironolactone did not reduce the incidence of major cardiovascular events.
Potassium binders for chronic hyperkalaemia in people with chronic kidney disease
The Cochrane database of systematic reviews (2020) · Meta analysis · n=688
Patiromer or sodium zirconium cyclosilicate may make little or no difference to death (any cause) (4 studies, 688 participants: RR 0.69, 95% CI 0.11, 4.32; I2 = 0%; low certainty evidence) in CKD.
Effects of Tribulus (Tribulus terrestris L.) Supplementation on Erectile Dysfunction and Testosterone Levels in Men-A Systematic Review of Clinical Trials
Nutrients (2025) · Systematic review · n=172
The Jadad score revealed low methodological quality for 50% of the studies.
Dietary Supplements for Erectile Dysfunction: Analysis of Marketed Products, Systematic Review, Meta-Analysis and Rational Use
Nutrients (2023) · Meta analysis
Based on the scoring system, 2 (8%) supplements matched with the cluster of higher expected efficacy, 3 (12%) with the lower efficacy cluster and 20 (80%) matched with the criterion of no expected efficacy.
Beneficial effects of natural products on female sexual dysfunction: A systematic review and meta-analysis
Phytomedicine : international journal of phytotherapy and phytopharmacology (2021) · Meta analysis · n=536
Panax ginseng was found to be effective in treating sexual arousal (SMD = 0.54, 95% CI = 0.11 - 0.97, p = 0.014) and sexual desire (SMD = 0.59, 95% CI = 0.27 - 0.90, p < 0.001) compared to placebo.
Both Potassium and Tribulus are closely matched — the best choice depends on your specific health goals.
For reduce inflammation, Potassium has a higher relevance score (85 vs 45).
No known interactions between Potassium and Tribulus have been documented in our database. However, always consult a healthcare provider before combining supplements.