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K8.5
Potassium – Forschung
Hilft vermutlich
185 begutachtete Studien
Was die Evidenz sagt
Hilft vermutlich
Potassium half in etwa der Hälfte (8/13) der Studien, die einen Effekt gemessen haben — vielversprechend, aber nicht einhellig.
Die meiste Evidenz stammt aus hochwertigen Meta-Analysen und randomisierten Studien, veröffentlicht 1965–2026 mit einer typischen Studiengröße von 923 Teilnehmenden.
Basierend auf 184 Studien · 25 Meta-Analysen · 145 RCTs · 350,935 Teilnehmende insgesamt
Konfidenz
Hohe Konfidenz
Was die Studien gefunden haben
8geholfen4unklar1nicht geholfen· 171 weitere ohne bewertete Effektdaten
Nach Outcome
Heart & blood pressureSenkt den Blutdruck und das Risiko für Herz-Kreislauf-Erkrankungen · 4-8 weeks
Hilft vermutlich106 Studien
Kidney & renal health
Hilft vermutlich11 Studien
Glucose & metabolic
Überwiegend Mechanismus / Beobachtung6 Studien
Therapeutic & clinical
Überwiegend Mechanismus / Beobachtung5 Studien
Kidney stones & urolithiasis
Überwiegend Mechanismus / Beobachtung3 Studien
Safety profile
Überwiegend Mechanismus / Beobachtung3 Studien
Weight management
Zu wenige bewertete Studien2 Studien
Bone health
Zu wenige bewertete Studien1 Studie
Cholesterol & lipidsSenkt den Blutdruck und das Risiko für Herz-Kreislauf-Erkrankungen · 4-8 weeks
Zu wenige bewertete Studien1 Studie
Women's health
Zu wenige bewertete Studien1 Studie
Energy & fatigueReduzierte Müdigkeit durch ausgeglichenen Elektrolythaushalt · 1-2 weeks
Zu wenige bewertete Studien1 Studie
In Zahlen
Aus 27 Studien mit messbaren Effekten gezogen
Wahrscheinlich echte Effekte
43%
über Studien hinweg
Untersuchte Personen
351k
typische Studie: 923 Personen
Stärkste Designs
170
25 gepoolt, 145 randomisiert
Zeigte Nutzen
62%
8/13 Studien
Wie lange Studien liefen
3+ Monate
3
Untersuchte Populationen
General population4
General population and hypertensive populations1
Healthy adults1
Adults with hypertension1
Stetige Forschung
47 Studien in den letzten 5 Jahren · Neueste Meta-Analyse: 2026
196519952026
1Meta-Analysen=237,036 · very large study2024
Einfach gesagt: Our study demonstrates significant positive associations between daily sodium intake (within the range of sodium intake between 2,000 and 7,500 mg/d), the sodium-potassium ratio, and risk of CVD and overall mortality, with women having stronger sodium-potassium ratio-mortality associations than men, and with the meta-analysis providing compelling support for the CVD associations.
2Blood pressure controlMeta-Analysen=2,500 · very large study2025
Einfach gesagt: This meta-analysis highlights the dose-response relationship between potassium supplementation and BP reduction, particularly in subjects with hypertension.
Granal M et al. · Clinical Kidney Journal (2025)
Dose-response analysis of RCTs from 2000-2024
Significant blood pressure reductions
Benefits most pronounced in hypertensive populations
6Global mean potassium intakeMeta-Analysen=104 · medium study2023
Einfach gesagt: Global mean potassium intake (2.25 g/day) falls below current guideline recommended intake level of > 3.5 g/day, with only 14% (95% CI 11-17%) of the global population achieving guideline-target mean intake.
Reddin C et al. · European journal of nutrition (2023)
Kein klarer Effekt
← SchlechterKein EffektBesser →
Approximately 31% (95% CI, 30-41%) of global population included have an estimated potassium intake > 2.5 g/day, with 14% (95% CI 11-17%) above 3.5 g/day.
Global mean potassium intake (2.25 g/day) falls below current guideline recommended intake level of > 3.5 g/day, with only 14% (95% CI 11-17%) of the global population achieving guideline-target mean intake.
There was considerable regional variation, with lowest mean potassium intake reported in Asia, and highest intake in Eastern and Western Europe.
14Blood pressure reductionMeta-Analysen=923 · large study2020
Einfach gesagt: Aerobic exercise, isometric training, low-sodium and high-potassium salt, comprehensive lifestyle modification, salt restriction, breathing-control, meditation and low-calorie diet also have obvious effects on BP reduction.
Fu J et al. · Journal of the American Heart Association (2020)
Among overweight and obese participants, low-calorie diet and low-calorie diet plus exercise could lower more BP than exercise.
Conclusions DASH might be the most effective intervention in lowering BP for adults with prehypertension to established hypertension.
Aerobic exercise, isometric training, low-sodium and high-potassium salt, comprehensive lifestyle modification, salt restriction, breathing-control, meditation and low-calorie diet also have obvious effects on BP reduction.
Liang YY, Zheng H, Chen CL, Guo H · Zhonghua Wai Ke Za Zhi (2012)
18Meta-Analyse2024
Einfach gesagt: Both supplements demonstrated greater reductions in SBP for the general population at lower dosages and longer treatment durations.
Behers BJ et al. · Nutrients (2024)
Both supplements demonstrated greater reductions in SBP for the general population at lower dosages and longer treatment durations.
Future studies are needed to validate these findings and provide tailored recommendations.
These studies could investigate varying dosages over long-term follow-up to provide robust data on optimal dosages and treatment durations, as our findings were limited due to reliance on previously published trials.
19Obesity and metabolic syndrome riskMeta-Analyse2016
Einfach gesagt: However, additional pertinent studies are needed to examine the underlying mechanism.
Cai X et al. · Nutrients (2016)
Kein klarer Effekt
← SchlechterKein EffektBesser →
The results of the pooled analysis and systematic review indicated that high potassium intake could not reduce the risk of obesity (pooled OR = 0.78; 95% CI: 0.61-1.01), while serum potassium and urinary sodium-to-potassium ratio was associated with obesity.
Potassium intake was associated with metabolic syndrome (pooled OR = 0.75; 95% CI: 0.50-0.97).
Nonlinear analysis also demonstrated a protective effect of adequate potassium intake on obesity and metabolic syndrome.
20Blood pressure reductionMeta-Analysen=1,430 · large study2026
Einfach gesagt: In patients with hypertension, the use of a salt substitute is associated with a significant reduction in both SBP and DBP compared with regular salt.
Kelly FA et al. · Arquivos brasileiros de cardiologia (2026)
Spürbar Nutzen
← SchlechterKein EffektBesser →
Likely real
Four RCTs involving 1,430 participants were included, of whom 725 (49.57%) received the salt substitute.
The use of a salt substitute was associated with a significant reduction in systolic BP (SBP) (MD, -5.75 mmHg; 95% CI, -6.98 to -2.39 mmHg; I2 = 37%; p < 0.01) and a significant reduction in diastolic BP (DBP) (MD, -1.62 mmHg; 95% CI, -2.34 to -0.91 mmHg; I2 = 0%; p < 0.001).
In patients with hypertension, the use of a salt substitute is associated with a significant reduction in both SBP and DBP compared with regular salt.