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Head-to-head evidence comparison — which supplement is right for you?
Resistant Starch wins 1 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Likely helps
17 of 19 studies with measurable effects showed benefit.
Top outcomes
Verdict
Likely helps
18 of 23 studies with measurable effects showed benefit.
Top outcomes
Shared outcomes (1)
Outcomes where both Resistant Starch and Selenium have evidence — compare verdict strength side-by-side.
15-30g daily
With meals, Divide throughout day for higher doses
Raw potato starch (unmodified) or green banana flour
100-200mcg
With food
Selenomethionine (best absorbed)
2-4 weeks
4-8 weeks
1-2 weeks
First 1-2 weeks
4-8 weeks
4-8 weeks
Metabolic Effects of Resistant Starch Type 2: A Systematic Literature Review and Meta-Analysis of Randomized Controlled Trials
Nutrients (2019) · Meta analysis · n=670
However, these outcomes were heavily influenced by positive results from a small number of individual studies which contradicted the conclusions of the majority of trials.
Acute Effects of Dietary Fiber in Starchy Foods on Glycemic and Insulinemic Responses: A Systematic Review of Randomized Controlled Crossover Trials
Nutrients (2023) · Systematic review
Data on insoluble DF and glucose metabolism are scarce.
The Effects of Resistant Starch on Biomarkers of Inflammation and Oxidative Stress: A Systematic Review and Meta-Analysis
Nutrition and cancer (2022) · Meta analysis · n=739
We used from the effect size, as estimated by the standardized mean difference (SMD) with 95% confidence intervals (95%CI) to perform the random method meta-analysis, with P value ≦0.05 as statistically significant.
Selenium, antioxidants, cardiovascular disease, and all-cause mortality: a systematic review and meta-analysis of randomized controlled trials
The American journal of clinical nutrition (2020) · Meta analysis · n=9423
However, a decreased risk with antioxidant mixtures was seen for CVD mortality when selenium was part of the mix (RR: 0.77; 95% CI: 0.62, 0.97; P = 0.02), with no association when selenium was absent.
Selenium for preventing cancer
The Cochrane database of systematic reviews (2018) · Meta analysis · n=27232
For analyses of RCTs with low risk of bias, the summary risk ratio (RR) for any cancer incidence was 1.01 (95% confidence interval (CI) 0.93 to 1.10; 3 studies, 19,475 participants; high-certainty evidence).
Selenium and prostate cancer: systematic review and meta-analysis
The American journal of clinical nutrition (2012) · Meta analysis · n=13254
Three high-quality studies included in the meta-analysis of toenail selenium and cancer risk indicated a reduction in prostate cancer risk (estimated RR: 0.29; 95% CI: 0.14, 0.61) with a toenail selenium concentration between 0.85 and 0.94 μg/g.
Meta-analysis showed modest 3.32 mg/dL reduction in fasting glucose. Effects were heavily influenced by small number of positive studies, with majority showing mixed results. Higher doses increase GI side effects.
Based on Cochrane systematic review showing moderate-certainty evidence for TPO antibody reduction. Effects on thyroid hormone levels (TSH, T4, T3) were inconsistent across studies.
AI-estimated from published studies. Interpret as directional guidance.
Resistant Starch has a higher evidence score (9/10 vs 9/10) and wins in 1 of 3 categories.
For reduce inflammation, Resistant Starch has a higher relevance score (85 vs 52).
No known interactions between Resistant Starch and Selenium have been documented in our database. However, always consult a healthcare provider before combining supplements.