Compare Supplements

Approved EPP regimen is a single 16 mg controlled-release SUBCUTANEOUS IMPLANT inserted by a clinician approximately every 60 days. There is NO consumer dose — afamelanotide is a prescription drug administered in a clinical setting, not a self-dosed supplement.

Any time

16 mg subcutaneous controlled-release implant (prescription, clinician-administered)

1000mg

With meals · with food (preferred)

Niacinamide tablets (500mg)

• Use outside a prescriber's care — afamelanotide is a prescription drug, not a self-administered supplement
• Pregnancy and breastfeeding (not established as safe)
• Personal history of melanoma or numerous/atypical moles without specialist oversight

• Photosensitizing medications / phototherapy
• Anticoagulants / antiplatelets

• Known hypersensitivity to niacin/niacinamide
• Severe hepatic impairment (caution at high doses)

• Carbamazepine / anticonvulsants