Compare Supplements

Prescription dosing is 75 mg or 150 mg subcutaneously every 2 weeks (a 300 mg every-4-weeks option exists), titrated by a clinician to the LDL-C target. A prescription drug; not a self-administered supplement regimen.

Any time

Subcutaneous prefilled pen/syringe (alirocumab)

Approved dose is 2 g twice daily (4 g/day total) taken with food, under a clinician, for statin-treated adults with elevated triglycerides and high cardiovascular risk. A prescription drug — not a self-directed regimen.

With meals · with food

Oral capsule — purified EPA ethyl ester (icosapent ethyl)

• Known serious hypersensitivity to alirocumab or excipients
• Pregnancy (limited data; lipid lowering generally deferred in pregnancy)

• Statins
• Other lipid-lowering agents (ezetimibe)

• Known hypersensitivity to icosapent ethyl or its components
• Caution with fish/shellfish allergy (limited data)
• Active serious bleeding

• Anticoagulants / antiplatelets (warfarin, DOACs, aspirin, clopidogrel)
• Antiarrhythmic drugs / rate-control agents