Compare Supplements

Prescription dosing is 75 mg or 150 mg subcutaneously every 2 weeks (a 300 mg every-4-weeks option exists), titrated by a clinician to the LDL-C target. A prescription drug; not a self-administered supplement regimen.

Any time

Subcutaneous prefilled pen/syringe (alirocumab)

500mg

Morning · with food (preferred)

Nicotinamide Riboside Chloride capsules or powder

• Known serious hypersensitivity to alirocumab or excipients
• Pregnancy (limited data; lipid lowering generally deferred in pregnancy)

• Statins
• Other lipid-lowering agents (ezetimibe)

• Known hypersensitivity to nicotinamide riboside or niacin derivatives
• Active cancer or cancer history: NAD+ elevation may theoretically support tumor cell metabolism (consult oncologist before use)
• Severe hepatic impairment: high-dose NAD+ precursors may affect liver metabolism

• Chemotherapy agents
• PARP inhibitors (e.g., olaparib, niraparib)
• Alcohol