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One AREDS2 daily regimen, usually split into two servings: vitamin C 500 mg, vitamin E 400 IU, lutein 10 mg, zeaxanthin 2 mg, zinc 80 mg (as zinc oxide) and copper 2 mg (as cupric oxide)

With meals · with food

A product matching the AREDS2 composition exactly: vitamin C 500 mg, vitamin E 400 IU, lutein 10 mg, zeaxanthin 2 mg, zinc 80 mg, copper 2 mg

6grams

Between meals

L-Arginine powder or capsules

• The ORIGINAL AREDS formula (containing beta-carotene) in anyone who currently smokes or has ever smoked — beta-carotene increased lung cancer incidence in ATBC (+18%) and CARET (RR 1.28), and doubled 10-year lung cancer odds in AREDS2 itself (OR 1.82)
• Concurrent use with other beta-carotene or high-dose vitamin A supplements in smokers and former smokers
• Wilson's disease or other copper-overload states (the formula supplies 2 mg copper)

• Other zinc-containing supplements or lozenges
• Copper supplements
• Anticoagulants and antiplatelets (warfarin, DOACs, aspirin)

• History of herpes (may reactivate outbreaks)
• Recent heart attack
• Low blood pressure

• Blood pressure medications
• Nitrates (nitroglycerin)
• PDE5 inhibitors (Viagra, etc.)