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One AREDS2 daily regimen, usually split into two servings: vitamin C 500 mg, vitamin E 400 IU, lutein 10 mg, zeaxanthin 2 mg, zinc 80 mg (as zinc oxide) and copper 2 mg (as cupric oxide)

With meals · with food

A product matching the AREDS2 composition exactly: vitamin C 500 mg, vitamin E 400 IU, lutein 10 mg, zeaxanthin 2 mg, zinc 80 mg, copper 2 mg

Prescription-only, clinician-titrated. Subcutaneous (Wegovy weight management: escalate to 2.4 mg once weekly; Ozempic diabetes: 0.5-2.0 mg once weekly). Oral (Rybelsus diabetes: 3-14 mg once daily). DO NOT self-dose.

Any time

Subcutaneous once-weekly injection (Ozempic / Wegovy)

• The ORIGINAL AREDS formula (containing beta-carotene) in anyone who currently smokes or has ever smoked — beta-carotene increased lung cancer incidence in ATBC (+18%) and CARET (RR 1.28), and doubled 10-year lung cancer odds in AREDS2 itself (OR 1.82)
• Concurrent use with other beta-carotene or high-dose vitamin A supplements in smokers and former smokers
• Wilson's disease or other copper-overload states (the formula supplies 2 mg copper)

• Other zinc-containing supplements or lozenges
• Copper supplements
• Anticoagulants and antiplatelets (warfarin, DOACs, aspirin)

• Personal or family history of medullary thyroid carcinoma (MTC)
• Multiple Endocrine Neoplasia syndrome type 2 (MEN2)
• Prior serious hypersensitivity to semaglutide or any GLP-1 receptor agonist

• Insulin and sulfonylureas
• Oral medications (general)
• Other GLP-1 receptor agonists