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Topical only. OTC cosmetic azelaic acid is typically around 10%; prescription strengths are 15% gel/foam (rosacea) and 20% cream (acne), applied as a thin layer to clean skin once or twice daily. There is no oral, injectable, or systemic dose. For rosacea or persistent acne, the prescription form under a clinician is the evidence-based route. This library does not provide an ingestion protocol.

Any time

Leave-on topical gel, foam, or cream (OTC ~10%, or prescription 15-20%)

Topical cosmetic only. Leave-on mandelic acid is used at roughly 5-10% in serums; professional peels use higher strengths (often a salicylic-mandelic combination). Apply to clean skin, building frequency as tolerated, with daily sunscreen. There is no oral or systemic dose — it is not ingested. This library does not provide an ingestion protocol.

Evening

Leave-on serum (≈5-10% mandelic acid) or a professional (salicylic-)mandelic peel

• For topical (skin) use only — not for ingestion, not for injection
• Known allergy or sensitivity to azelaic acid or formulation excipients
• Application to broken, severely irritated, or compromised skin until healed

• Other strong leave-on actives (retinoids, AHAs/BHAs, benzoyl peroxide)

• For topical (skin) use only — not for ingestion, not for injection
• Known allergy or sensitivity to AHAs
• Active dermatitis or broken/sunburned skin until healed

• Other leave-on actives (retinoids, other acids)