Compare Supplements

Topical only. OTC cosmetic azelaic acid is typically around 10%; prescription strengths are 15% gel/foam (rosacea) and 20% cream (acne), applied as a thin layer to clean skin once or twice daily. There is no oral, injectable, or systemic dose. For rosacea or persistent acne, the prescription form under a clinician is the evidence-based route. This library does not provide an ingestion protocol.

Any time

Leave-on topical gel, foam, or cream (OTC ~10%, or prescription 15-20%)

Topical cosmetic only. Niacinamide is typically formulated at 2-5% in leave-on serums, creams, or gels and applied to clean skin once or twice daily (AM and/or PM). It layers well under sunscreen and with most other actives. There is no oral, injectable, or systemic dose in this cosmetic context — it is not ingested here. This library does not provide an ingestion protocol.

Any time

Leave-on topical serum or cream (2-5% niacinamide)

• For topical (skin) use only — not for ingestion, not for injection
• Known allergy or sensitivity to azelaic acid or formulation excipients
• Application to broken, severely irritated, or compromised skin until healed

• Other strong leave-on actives (retinoids, AHAs/BHAs, benzoyl peroxide)

• For topical (skin) use only — not for ingestion, not for injection (in this cosmetic context)
• Known allergy or sensitivity to niacinamide or formulation excipients
• Application to broken, irritated, or compromised skin until healed

• Pure ascorbic acid (vitamin C) at low pH
• Strong leave-on exfoliating actives (AHAs/BHAs, retinoids)