Compare Supplements

Side-by-side comparison of 2 supplements

Bcg5.0

B. coagulans

High safety

Bla6.0

B. lactis (BB-12 / HN019)

High safety

Evidence

Mostly mechanism / observational

Evidence Score5/10

Studies: 27

Meta-analyses: 2

Mostly mechanism / observational

Evidence Score6/10

Studies: 23

Meta-analyses: 4

Dosage & timing

Dosage:

1-2 billion CFU (spores) daily. The IBS-D and gas/bloating trials used 2 x 10^9 CFU/day of MTCC 5856 (LactoSpore); the GBI-30 6086 (BC30) studies used 1 x 10^9 CFU/day.

Best Time:

Any time

Can take on empty stomach

Form:

Tablet or capsule delivering a named strain — MTCC 5856 (LactoSpore) for IBS, GBI-30 6086 (BC30) for the exercise and amino-acid claims

Dosage:

1-10 billion CFU daily for BB-12 (1 billion is enough); 10-20 billion CFU daily for HN019 if transit is the goal

Best Time:

Any time · with food

Take with food

Form:

Capsule or sachet standardized to a named strain (BB-12 or HN019)

What you'll notice

🌀 Relief in diarrhoea-predominant IBSpositive

4-12 weeks

💨 Less functional gas and bloatingpositive

4 weeks

🚫 No benefit for constipationnegative

n/a

⏱️ Faster whole-gut transitpositive

2 weeks

🚽 Slightly more frequent bowel movementspositive

4 weeks

🚫 Not a treatment for functional constipationnegative

n/a

Safety

High safety

Contraindications:

Immunocompromise or critical illness (a general precaution for live bacterial products; no trial enrolled such patients)

Drug Interactions:

Systemic antibiotics

Side Effects:

Mild gas or digestive upset

High safety

Contraindications:

Immunocompromise or immunosuppression (class-level precaution for live probiotics)
Critical illness or indwelling central venous catheter

Drug Interactions:

Systemic antibiotics

Side Effects:

Mild transient digestive changes

Works well with

Probiotics

complementary

Saccharomyces boulardii

complementary

Inulin

complementary

Probiotics

complementary

L. casei Shirota

complementary

How they work together

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