Compare Supplements

1-2 billion CFU (spores) daily. The IBS-D and gas/bloating trials used 2 x 10^9 CFU/day of MTCC 5856 (LactoSpore); the GBI-30 6086 (BC30) studies used 1 x 10^9 CFU/day.

Any time

Tablet or capsule delivering a named strain — MTCC 5856 (LactoSpore) for IBS, GBI-30 6086 (BC30) for the exercise and amino-acid claims

One 65-100 mL bottle of the fermented milk drink daily, delivering roughly 6.5 x 10^9 to 1 x 10^11 CFU depending on the product. Doses across trials span this whole range with no dose-comparison study to separate them.

Any time

Fermented milk drink containing L. casei Shirota (Yakult), 65-100 mL daily

• Immunocompromise or critical illness (a general precaution for live bacterial products; no trial enrolled such patients)

• Systemic antibiotics

• Immunocompromise or immunosuppression (class-level precaution for live probiotics)
• Critical illness or indwelling central venous catheter

• Proton pump inhibitors