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Topical cosmetic only. Bakuchiol is typically formulated around 0.5-1% in leave-on serums or creams and applied to clean skin once or twice daily. Unlike retinol it is not photolabile, so it can be used AM or PM, though daily sunscreen is still recommended. There is no oral, injectable, or systemic dose — it is not ingested. This library does not provide an ingestion protocol.

Any time

Leave-on topical serum or cream (0.5-1% purified bakuchiol)

Prescription topical: a pea-sized amount of 0.025%-0.1% cream or gel applied to clean, dry skin once nightly. Start low-strength and every-other-night to build tolerance. A prescription drug used under clinician direction — not a supplement regimen.

Before bed

Topical cream or gel, 0.025%-0.1% (prescription)

• For topical (skin) use only — not for ingestion, not for injection
• Known allergy or sensitivity to bakuchiol or formulation excipients
• Application to broken, irritated, or compromised skin until healed

• Other leave-on actives (retinoids, acids)

• Pregnancy and planning pregnancy (topical retinoid — avoid)
• Breastfeeding (avoid application near areas of infant contact)
• Eczema / rosacea-prone or broken/sunburned skin (irritation)

• Benzoyl peroxide
• Other topical exfoliants (AHAs / BHAs, abrasives)
• Photosensitizing drugs