Compare Supplements

180 mg orally once daily, with or without food, under a clinician. Available alone (Nexletol) or co-formulated with ezetimibe 10 mg (Nexlizet). A prescription drug — dosing is set by a prescriber.

Any time

Oral tablet (bempedoic acid 180 mg)

10 mg once daily, with or without food, alone or added to a statin — under a clinician. A prescription drug; not a self-directed supplement regimen.

Any time

Oral tablet (ezetimibe 10 mg)

• Concurrent simvastatin >20 mg or pravastatin >40 mg (bempedoic acid raises their levels)
• Active gout flare without management
• History of tendon rupture related to similar agents

• Simvastatin / pravastatin
• Corticosteroids / fluoroquinolones

• Active liver disease or unexplained persistent transaminase elevations (when combined with a statin)
• Pregnancy and breastfeeding (especially in combination with a statin)
• Known hypersensitivity to ezetimibe

• Bile-acid sequestrants (cholestyramine, colesevelam)
• Statins
• Cyclosporine