Compare Supplements

1 x 10^8 CFU (100 million) daily — the dose that won the only head-to-head dose comparison; 1 x 10^10 CFU also beat placebo in a separate trial, so higher doses are not ruled out

Any time

Freeze-dried capsule standardized to 35624 at 1 x 10^8 CFU

1 x 10^9 to 1 x 10^10 CFU daily — the two trials that state a dose used 1 x 10^10 CFU/day (depression) and a minimum of 1 x 10^9 CFU/day (pregnancy). Neither found a benefit on its primary endpoint, so this is the dose range that has been tested, not a dose shown to work.

Any time

Freeze-dried capsule or sachet standardized to B. longum 1714

• Immunocompromise or immunosuppression (class-level precaution for live probiotics)
• Critical illness or indwelling central venous catheter

• Lactulose breath testing

• Immunocompromise or immunosuppression (class-level precaution for live probiotics)
• Critical illness or indwelling central venous catheter

• Systemic antibiotics
• Immunosuppressants