Compare Supplements

Side-by-side comparison of 2 supplements

Bla6.0

B. lactis (BB-12 / HN019)

High safety

LF6.3

Lactoferrin

Moderate safety

Evidence

Mostly mechanism / observational

Evidence Score6/10

Studies: 19

Meta-analyses: 4

Mostly mechanism / observational

Evidence Score6.3/10

Studies: 64

Meta-analyses: 8

Dosage & timing

Dosage:

1-10 billion CFU daily for BB-12 (1 billion is enough); 10-20 billion CFU daily for HN019 if transit is the goal

Best Time:

Any time · with food

Take with food

Form:

Capsule or sachet standardized to a named strain (BB-12 or HN019)

Dosage:

300mg

Best Time:

Between meals

Can take on empty stomach

Form:

Bovine lactoferrin capsule or powder (≥95% purity)

What you'll notice

⏱️ Faster whole-gut transitpositive

2 weeks

🚽 Slightly more frequent bowel movementspositive

4 weeks

🚫 Not a treatment for functional constipationnegative

n/a

🛡️ Fewer Respiratory Infectionspositive

4–8 weeks of use

🩸 Improved Iron Statuspositive

4–8 weeks

🔥 Lower Inflammatory Markerspositive

4–8 weeks

Safety

High safety

Contraindications:

Immunocompromise or immunosuppression (class-level precaution for live probiotics)
Critical illness or indwelling central venous catheter

Drug Interactions:

Systemic antibiotics

Side Effects:

Mild transient digestive changes

Moderate safety

Contraindications:

Known allergy to bovine milk proteins (risk of cross-reactivity)
Hemochromatosis or iron overload conditions (holo-lactoferrin form could worsen iron loading)
Active malignancy — theoretical concern due to growth-promoting activity on epithelial cells (consult oncologist)

Drug Interactions: