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1 x 10^9 to 1 x 10^10 CFU daily — the two trials that state a dose used 1 x 10^10 CFU/day (depression) and a minimum of 1 x 10^9 CFU/day (pregnancy). Neither found a benefit on its primary endpoint, so this is the dose range that has been tested, not a dose shown to work.
Any time
Freeze-dried capsule or sachet standardized to B. longum 1714
3 x 10^9 CFU daily of the fixed combination (L. helveticus R0052 plus B. longum R0175) — the dose used in the founding trial, the dancer trial and the open-label MDD study. No dose-comparison study exists.
Any time
Fixed two-strain sachet or capsule: L. helveticus R0052 plus B. longum R0175 at 3 x 10^9 CFU
4 weeks
8 weeks
n/a
8 weeks
3 weeks
n/a
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