Compare Supplements

Side-by-side comparison of 2 supplements

Bor3.5

Borage Oil

Moderate safety

Epo7.5

Evening Primrose Oil

High safety

Evidence

Evidence Score3.5/10

Studies: 4

Meta-analyses: 0

Evidence Score7.5/10

Studies: 24

Meta-analyses: 13

Outcome Grades

Improve skin healthF

Reduce inflammationF

Improve skin healthC

Reduce inflammationC

A-F grade per outcome, combining overall evidence with goal-specific relevance. A = strong evidence; F = insufficient. Hover a badge for details.

Dosage & timing

Dosage:

1-3g/day borage oil providing roughly 240-1400mg GLA (higher GLA doses used in RA trials)

Best Time:

With meals · with food

Take with food

Form:

Borage oil softgels (standardized GLA, PA-free)

Dosage:

2500mg

Best Time:

With meals · with food

Take with food

Form:

Softgels (cold-pressed oil)

What you'll notice

🦴 Modest joint-symptom relief (RA)40%

3-6 months

🚫 No benefit for eczema100%

Throughout use

💧 Skin-barrier improvement35%

6-12 weeks

💫 Reduced Breast Tenderness55%

2-3 cycles

✨ PMS Symptom Relief50%

2-3 cycles

✨ Skin Improvement50%

8-12 weeks

Safety

Moderate safety

Contraindications:

Pregnancy (GLA/prostaglandin effects; possible labor-inducing concern)
Seizure disorders or use of seizure-threshold-lowering drugs (theoretical)
Liver disease (pyrrolizidine alkaloid concern with non-PA-free products)

Drug Interactions:

Anticoagulants / antiplatelets
Phenothiazines / drugs lowering seizure threshold
NSAIDs

Side Effects:

Mild GI upset (soft stools, nausea, belching)HeadacheLiver toxicity from pyrrolizidine alkaloids (non-PA-free products)

High safety

Contraindications:

Seizure disorders (may lower seizure threshold)
Before surgery (stop 2 weeks prior)

Drug Interactions:

Blood thinners
Anticonvulsants
Phenothiazines

Side Effects:

GI upsetHeadacheSoft stools

Works well with

complementary

complementary

complementary

complementary

complementary

How they work together

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