Compare Supplements

Side-by-side comparison of 2 supplements

CA8.0

Calcium

Moderate safety

HCG5.5

HCG (Human Chorionic Gonadotropin)

Limited safety

Evidence

Likely helps

Evidence Score8/10

Studies: 118

Meta-analyses: 37

Mostly mechanism / observational

Evidence Score5.5/10

Studies: 7

Meta-analyses: 1

Dosage & timing

Dosage:

1200mg

Best Time:

Split through the day · with food

Take with food

Form:

Calcium Citrate

Dosage:

Prescription-only and indication-dependent. For fertility preservation / intratesticular-testosterone maintenance on TRT, small studies used ~125-500 IU subcutaneously every other day. For spermatogenesis induction in hypogonadotropic hypogonadism, typically ~1,000-2,500 IU two to three times weekly (often combined with FSH), titrated to response. For female ovulation/oocyte-maturation trigger, a single dose (~5,000-10,000 IU urinary or 250 µg recombinant). No dietary-supplement dose exists.

Best Time:

Any time

Can take on empty stomach

Form:

Prescription hCG — recombinant (choriogonadotropin alfa) or urinary-derived, by injection

What you'll notice

🦴 Improved Bone Mineral Densitypositive

6-24 months

🛡️ Reduced Fracture Riskpositive

12-36 months

🤱 Preeclampsia Prevention in Pregnancypositive

Throughout pregnancy

🧪 Maintains intratesticular testosterone on TRT (randomized dose-response)positive

Weeks

👶 Preserves spermatogenesis during testosterone therapypositive

Months

🔬 Induces spermatogenesis in hypogonadotropic menpositive

Months

Safety

Moderate safety

Contraindications:

Hypercalcemia (elevated blood calcium) — calcium supplementation is absolutely contraindicated
Hypercalciuria (elevated urinary calcium excretion) without medical supervision
Primary hyperparathyroidism without medical supervision

Drug Interactions:

Bisphosphonates (alendronate, risedronate)
Levothyroxine (thyroid hormone)
Tetracycline antibiotics (doxycycline, tetracycline)

Side Effects:

ConstipationBloating and gasNausea

Limited safety

Contraindications:

Hormone-sensitive tumors (e.g. prostate, breast) or other androgen/estrogen-dependent conditions
Known hypersensitivity to hCG
Use without medical supervision

Drug Interactions:

Exogenous testosterone / anabolic steroids
FSH / hMG (menotropins)
Aromatase inhibitors (e.g. anastrozole)

Side Effects:

Injection-site reaction (pain, redness, swelling)Estradiol elevation / gynecomastia / water retention (men)Ovarian hyperstimulation syndrome (women)

Works well with

Vitamin D3

enhances

Vitamin K2

complementary

Magnesium

complementary

No synergies listed

How they work together

Like what you see? Add these to your stack.

See how they work together through biological pathways.

Build Your Stack

Want to compare more supplements?

Loading comparison...