Compare Supplements

Side-by-side comparison of 2 supplements

Cu5.5

Copper

Moderate safety

Vk6.0

Vitamin K2

Moderate safety

Evidence

Evidence Score5.5/10

Studies: 57

Meta-analyses: 20

Evidence Score6/10

Studies: 55

Meta-analyses: 9

Outcome Grades

Bone healthC

Prenatal supportC

Bone healthB

Prenatal supportC

A-F grade per outcome, combining overall evidence with goal-specific relevance. A = strong evidence; F = insufficient. Hover a badge for details.

Pooled effect-size head-to-headBeta

Direct side-by-side from the meta-analysis. Each row is an outcome where ≥2 of your selected supplements have pooled data. Best effect per row highlighted.

Outcome	Copper	Vitamin K2
Bone health — Bone Mineral Density + better · % BMD change	+0.0 weak	+0.9best weak

Click an outcome to see the full ranked table on the goal page.

Dosage & timing

Dosage:

1-2mg daily (typically to balance zinc)

Best Time:

With meals · with food (preferred)

Take with food

Form:

Copper Bisglycinate (gentle, well-absorbed)

Dosage:

180mcg

Best Time:

With meals · with food

Take with food

Form:

MK-7 (menaquinone-7)

What you'll notice

⚖️ Zinc Balancepositive

Ongoing

⚡ Energy Supportpositive

4-8 weeks

⚠️ Toxicity Risktrade-off

With chronic excess

🦴 Improved Bone Healthpositive

6-12 months

❤️ Cardiovascular Supportpositive

1-3 years

Safety

Moderate safety

Contraindications:

Wilson's disease (copper accumulation disorder)
Hereditary copper toxicity conditions

Drug Interactions:

Zinc supplements
Penicillamine

Side Effects:

NauseaLiver issues (excess)

Moderate safety

Contraindications:

Those taking warfarin or other vitamin K antagonists (consult doctor)
Anticoagulant or blood thinner therapy (warfarin, heparin, Coumadin) — Vitamin K2 directly antagonizes warfarin's mechanism of action

Drug Interactions: